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Viruses 2010, 2(8), 1564-1570; doi:10.3390/v2081564
Short Note

Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report

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Received: 24 June 2010 / Revised: 16 July 2010 / Accepted: 28 July 2010 / Published: 29 July 2010
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Abstract

A first case of clinical tenofovir (TDF) HBV resistance in an HIV/HBV coinfected patient who developed an acute flare of hepatitis B is reported. The clinical course was accompanied by signs of acute liver failure after being on successful HBV treatment with tenofovir and persistently undetectable HBV-DNA viral load for over five years.
Keywords: HIV-HBV-coinfection; tenofovir; clinical HBV resistance HIV-HBV-coinfection; tenofovir; clinical HBV resistance
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Schewe, K.; Noah, C.; Sirma, H.; Schmiedel, S.; van Lunzen, J.; Rockstroh, J.K.; Schildgen, O. Is there Emergence of Clinical HBV Resistance Under Long-Term HBV Combination Therapy? A Challenging Case Report. Viruses 2010, 2, 1564-1570.

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