Seroconversion to HCoV-NL63 in Rhesus Macaques
AbstractHCoV-NL63 is a recently identified respiratory virus. Its pathogenesis has not been fully unraveled because an animal model is currently lacking. Here we examined whether rhesus macaques encounter HCoV-NL63 infections during life, by examining the levels of antibodies to HCoV-NL63 in time. The animals were followed for 7 up till 19 years, and in three animals we observed a steep rise in antibodies during follow up, indicative of a natural infection with HCoV-NL63.
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Dijkman, R.; Mulder, H.L.; Rumping, L.; Kraaijvanger, I.; Deijs, M.; Jebbink, M.F.; Verschoor, E.J.; Van der Hoek, L. Seroconversion to HCoV-NL63 in Rhesus Macaques. Viruses 2009, 1, 647-656.
Dijkman R, Mulder HL, Rumping L, Kraaijvanger I, Deijs M, Jebbink MF, Verschoor EJ, Van der Hoek L. Seroconversion to HCoV-NL63 in Rhesus Macaques. Viruses. 2009; 1(3):647-656.Chicago/Turabian Style
Dijkman, Ronald; Mulder, H. Lie; Rumping, Lynne; Kraaijvanger, Ilse; Deijs, Martin; Jebbink, Maarten F.; Verschoor, Ernst J.; Van der Hoek, Lia. 2009. "Seroconversion to HCoV-NL63 in Rhesus Macaques." Viruses 1, no. 3: 647-656.