Viruses 2009, 1(3), 647-656; doi:10.3390/v1030647
Communication

Seroconversion to HCoV-NL63 in Rhesus Macaques

1email, 1email, 1email, 1email, 1email, 1email, 2email and 1,* email
Received: 26 August 2009; in revised form: 28 October 2009 / Accepted: 30 October 2009 / Published: 30 October 2009
(This article belongs to the Special Issue Newly Identified Respiratory Viruses)
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Abstract: HCoV-NL63 is a recently identified respiratory virus. Its pathogenesis has not been fully unraveled because an animal model is currently lacking. Here we examined whether rhesus macaques encounter HCoV-NL63 infections during life, by examining the levels of antibodies to HCoV-NL63 in time. The animals were followed for 7 up till 19 years, and in three animals we observed a steep rise in antibodies during follow up, indicative of a natural infection with HCoV-NL63.
Keywords: HCoV-NL63; rhesus macaques
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Dijkman, R.; Mulder, H.L.; Rumping, L.; Kraaijvanger, I.; Deijs, M.; Jebbink, M.F.; Verschoor, E.J.; Van der Hoek, L. Seroconversion to HCoV-NL63 in Rhesus Macaques. Viruses 2009, 1, 647-656.

AMA Style

Dijkman R, Mulder HL, Rumping L, Kraaijvanger I, Deijs M, Jebbink MF, Verschoor EJ, Van der Hoek L. Seroconversion to HCoV-NL63 in Rhesus Macaques. Viruses. 2009; 1(3):647-656.

Chicago/Turabian Style

Dijkman, Ronald; Mulder, H. Lie; Rumping, Lynne; Kraaijvanger, Ilse; Deijs, Martin; Jebbink, Maarten F.; Verschoor, Ernst J.; Van der Hoek, Lia. 2009. "Seroconversion to HCoV-NL63 in Rhesus Macaques." Viruses 1, no. 3: 647-656.


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