Nanomaterials-Based Fluorimetric Methods for MicroRNAs Detection
AbstractMicroRNAs (miRNAs) are small endogenous non-coding RNAs of ~22 nucleotides that play important functions in the regulation of many biological processes, including cell proliferation, differentiation, and death. Since their expression has been in close association with the development of many diseases, recently, miRNAs have been regarded as clinically important biomarkers and drug discovery targets. However, because of the short length, high sequence similarity and low abundance of miRNAs in vivo, it is difficult to realize the sensitive and selective detection of miRNAs with conventional methods. In line with the rapid development of nanotechnology, nanomaterials have attracted great attention and have been intensively studied in biological analysis due to their unique chemical, physical and size properties. In particular, fluorimetric methodologies in combination with nanotechnology are especially rapid, sensitive and efficient. The aim of this review is to provide insight into nanomaterials-based fluorimetric methods for the detection of miRNAs, including metal nanomaterials, quantum dots (QDs), graphene oxide (GO) and silicon nanoparticles. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
La, M.; Liu, L.; Zhou, B.-B. Nanomaterials-Based Fluorimetric Methods for MicroRNAs Detection. Materials 2015, 8, 2809-2829.
La M, Liu L, Zhou B-B. Nanomaterials-Based Fluorimetric Methods for MicroRNAs Detection. Materials. 2015; 8(5):2809-2829.Chicago/Turabian Style
La, Ming; Liu, Lin; Zhou, Bin-Bin. 2015. "Nanomaterials-Based Fluorimetric Methods for MicroRNAs Detection." Materials 8, no. 5: 2809-2829.