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Materials 2015, 8(3), 1162-1175; doi:10.3390/ma8031162

Microstructure Evolution and Mechanical Properties Improvement in Liquid-Phase-Sintered Hydroxyapatite by Laser Sintering

1
Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China
2
State Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, China
3
Orthopedic Biomedical Materials Institute, Central South University, Changsha 410083, China
4
Department of Orthopedics, the Second Xiangya Hospital, Central South University, Changsha 410011, China
5
School of Materials Science and Engineering, Central South University, Changsha 410083, China
6
School of Basic Medical Science, Central South University, Changsha 410078, China
*
Author to whom correspondence should be addressed.
Academic Editor: Andrew J. Ruys
Received: 22 January 2015 / Revised: 4 March 2015 / Accepted: 11 March 2015 / Published: 17 March 2015
(This article belongs to the Special Issue Bioceramics)
View Full-Text   |   Download PDF [1593 KB, uploaded 17 March 2015]   |  

Abstract

CaO-Al2O3-SiO2 (CAS) as a liquid phase was introduced into hydroxyapatite (HAp) to prepare bone scaffolds. The effects of the CAS content (1, 2, 3, 4 and 5 wt%) on microstructure and mechanical properties of HAp ceramics were investigated. The optimal compression strength, fracture toughness and Vickers hardness reached 22.22 MPa, 1.68 MPa·m1/2 and 4.47 GPa when 3 wt% CAS was added, which were increased by 105%, 63% and 11% compared with those of HAp ceramics without CAS, respectively. The improvement of the mechanical properties was attributed to the improved densification, which was caused by the solid particle to rearrange during liquid phase sintering. Moreover, simulated body fluid (SBF) study indicated the HAp ceramics could maintain the mechanical properties and form a bone-like apatite layer when they were immersed in SBF. Cell culture was used to evaluate biocompatibility of the HAp ceramics. The results demonstrated MG-63 cells adhered and spread well. View Full-Text
Keywords: liquid phase sintering; laser sintering; microstructure; mechanical properties; hydroxyapatite liquid phase sintering; laser sintering; microstructure; mechanical properties; hydroxyapatite
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Duan, S.; Feng, P.; Gao, C.; Xiao, T.; Yu, K.; Shuai, C.; Peng, S. Microstructure Evolution and Mechanical Properties Improvement in Liquid-Phase-Sintered Hydroxyapatite by Laser Sintering. Materials 2015, 8, 1162-1175.

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