Scaffold Characteristics for Functional Hollow Organ Regeneration
AbstractMany medical conditions require surgical reconstruction of hollow organs. Tissue engineering of organs and tissues is a promising new technique without harvest site morbidity. An ideal biomaterial should be biocompatible, support tissue formation and provide adequate structural support. It should degrade gradually and provide an environment allowing for cell-cell interaction, adhesion, proliferation, migration, and differentiation. Although tissue formation is feasible, functionality has never been demonstrated. Mainly the lack of proper innervation and vascularisation are hindering contractility and normal function. In this chapter we critically review the current state of engineering hollow organs with a special focus on innervation and vascularisation.
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Horst, M.; Madduri, S.; Gobet, R.; Sulser, T.; Hall, H.; Eberli, D. Scaffold Characteristics for Functional Hollow Organ Regeneration. Materials 2010, 3, 241-263.
Horst M, Madduri S, Gobet R, Sulser T, Hall H, Eberli D. Scaffold Characteristics for Functional Hollow Organ Regeneration. Materials. 2010; 3(1):241-263.Chicago/Turabian Style
Horst, Maya; Madduri, Srinivas; Gobet, Rita; Sulser, Tullio; Hall, Heike; Eberli, Daniel. 2010. "Scaffold Characteristics for Functional Hollow Organ Regeneration." Materials 3, no. 1: 241-263.