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Materials 2010, 3(2), 999-1014; doi:10.3390/ma3020999

A Review of Keratin-Based Biomaterials for Biomedical Applications

Wake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, North Carolina, USA
* Author to whom correspondence should be addressed.
Received: 6 January 2009 / Revised: 24 January 2010 / Accepted: 26 January 2010 / Published: 3 February 2010
(This article belongs to the Special Issue Advances in Biomaterials)
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Advances in the extraction, purification, and characterization of keratin proteins from hair and wool fibers over the past century have led to the development of a keratin-based biomaterials platform. Like many naturally-derived biomolecules, keratins have intrinsic biological activity and biocompatibility. In addition, extracted keratins are capable of forming self-assembled structures that regulate cellular recognition and behavior. These qualities have led to the development of keratin biomaterials with applications in wound healing, drug delivery, tissue engineering, trauma and medical devices. This review discusses the history of keratin research and the advancement of keratin biomaterials for biomedical applications.
Keywords: keratin; human hair protein; natural biomaterial; protein film; scaffold keratin; human hair protein; natural biomaterial; protein film; scaffold
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Rouse, J.G.; Van Dyke, M.E. A Review of Keratin-Based Biomaterials for Biomedical Applications. Materials 2010, 3, 999-1014.

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