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Materials 2009, 2(4), 1480-1507; doi:10.3390/ma2041480
Review

Biocompatibility of Different Nerve Tubes

1,* , 2
 and
3
1 Department of Plastic, Reconstructive and Hand Surgery, University of Luebeck, 23538 Luebeck, Germany 2 Institute of Biochemistry and Cell Biology, University of Magdeburg, 39120 Magdeburg, Germany 3 Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Klinikum Bielefeld-Mitte, 33604 Bielefeld, Germany
* Author to whom correspondence should be addressed.
Received: 27 August 2009 / Revised: 24 September 2009 / Accepted: 25 September 2009 / Published: 30 September 2009
(This article belongs to the Special Issue Biocompatibility of Materials)
Download PDF [2567 KB, uploaded 30 September 2009]

Abstract

Bridging nerve gaps with suitable grafts is a major clinical problem. The autologous nerve graft is considered to be the gold standard, providing the best functional results; however, donor site morbidity is still a major disadvantage. Various attempts have been made to overcome the problems of autologous nerve grafts with artificial nerve tubes, which are “ready-to-use” in almost every situation. A wide range of materials have been used in animal models but only few have been applied to date clinically, where biocompatibility is an inevitable prerequisite. This review gives an idea about artificial nerve tubes with special focus on their biocompatibility in animals and humans.
Keywords: nerve tube; nerve repair; biocompatibility; artificial nerve; peripheral nerve nerve tube; nerve repair; biocompatibility; artificial nerve; peripheral nerve
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Stang, F.; Keilhoff, G.; Fansa, H. Biocompatibility of Different Nerve Tubes. Materials 2009, 2, 1480-1507.

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