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Materials, Volume 1, Issue 1 (December 2008), Pages 1-43

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Editorial

Jump to: Research

Open AccessEditorial Welcome to Materials – a New Open Access Journal for a Growing Scientific Community
Materials 2008, 1(1), 1-2; doi:10.3390/ma1010001
Received: 28 August 2008 / Published: 29 August 2008
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Research

Jump to: Editorial

Open AccessArticle Lessons from a “Failed” Experiment: Zinc Silicates with Complex Morphology by Reaction of Zinc Acetate, the Ionic Liquid Precursor (ILP) Tetrabutylammonium Hydroxide (TBAH), and Glass
Materials 2008, 1(1), 3-24; doi:10.3390/ma1010003
Received: 25 July 2008 / Accepted: 8 August 2008 / Published: 29 August 2008
Cited by 9 | PDF Full-text (2483 KB) | HTML Full-text | XML Full-text
Abstract
At elevated temperatures, the ionic liquid precursor (ILP) tetrabutylammonium hydroxide reacts with zinc acetate and the glass wall of the reaction vessel. While the reaction of OH- with the glass wall is not surprising as such and could be considered a failed
[...] Read more.
At elevated temperatures, the ionic liquid precursor (ILP) tetrabutylammonium hydroxide reacts with zinc acetate and the glass wall of the reaction vessel. While the reaction of OH- with the glass wall is not surprising as such and could be considered a failed experiment, the resulting materials are interesting for a variety of applications. If done on purpose and under controlled conditions, the reaction with the glass wall results in uniform, well-defined hemimorphite Zn4Si2O7(OH)2·nH2O and willemite Zn2SiO4 microcrystals and films. Their morphology can be adjusted by variation of the reaction time and reaction temperature. The hemimorphite can be transformed to Zn2SiO4 via calcination. The process is therefore a viable approach for the fabrication of porous films on glass surfaces with potential applications as catalyst support, among others. Full article
Open AccessArticle Modulating the Release Kinetics of Paclitaxel from Membrane-Covered Stents Using Different Loading Strategies
Materials 2008, 1(1), 25-43; doi:10.3390/ma1010025
Received: 7 October 2008 / Revised: 5 November 2008 / Accepted: 6 November 2008 / Published: 7 November 2008
Cited by 4 | PDF Full-text (6413 KB) | HTML Full-text | XML Full-text
Abstract
Membrane-covered Express2TM Monorail® stents composed of chitosan (CH) blended with polyethylene oxide (PEO) in 70:30% wt (CH-PEO) were coated with a monolayer of hyaluronic acid (HA). This significantly improved the resistance to platelet adhesion and demonstrated excellent mechanical properties, resisting the
[...] Read more.
Membrane-covered Express2TM Monorail® stents composed of chitosan (CH) blended with polyethylene oxide (PEO) in 70:30% wt (CH-PEO) were coated with a monolayer of hyaluronic acid (HA). This significantly improved the resistance to platelet adhesion and demonstrated excellent mechanical properties, resisting the harsh conditions during stent crimping and subsequent inflation. CH-PEO/HA membrane was then combined with a paclitaxel (Pac) delivery system via three different approaches for comparison of release profiles of Pac. The activity of Pac in these systems was confirmed since its presence in the membrane significantly decreased cell viability of U937 macrophages. Presented results are promising for applications requiring different release patterns of hydrophobic drugs. Full article
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