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Int. J. Environ. Res. Public Health 2016, 13(11), 1057; doi:10.3390/ijerph13111057

Pediatric Exposures to Ionizing Radiation: Carcinogenic Considerations

1
Department of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
2
Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
*
Authors to whom correspondence should be addressed.
Academic Editors: Helena Solo-Gabriele and Alesia Ferguson
Received: 29 June 2016 / Revised: 24 October 2016 / Accepted: 26 October 2016 / Published: 28 October 2016
(This article belongs to the Special Issue Children’s Exposure to Environmental Contaminants)
View Full-Text   |   Download PDF [305 KB, uploaded 28 October 2016]

Abstract

Children are at a greater risk than adults of developing cancer after being exposed to ionizing radiation. Because of their developing bodies and long life expectancy post-exposure, children require specific attention in the aftermath of nuclear accidents and when radiation is used for diagnosis or treatment purposes. In this review, we discuss the carcinogenic potential of pediatric exposures to ionizing radiation from accidental, diagnostic, and therapeutic modalities. Particular emphasis is given to leukemia and thyroid cancers as consequences of accidental exposures. We further discuss the evidence of cancers that arise as a result of radiotherapy and conclude the review with a summary on the available literature on the links between computer tomography (CT) and carcinogenesis. Appropriate actions taken to mitigate or minimize the negative health effects of pediatric exposures to ionizing radiation and future considerations are discussed. View Full-Text
Keywords: radiation; children’s health; cancer; computed tomography radiation; children’s health; cancer; computed tomography
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Kutanzi, K.R.; Lumen, A.; Koturbash, I.; Miousse, I.R. Pediatric Exposures to Ionizing Radiation: Carcinogenic Considerations. Int. J. Environ. Res. Public Health 2016, 13, 1057.

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