A Concurrent Exposure to Arsenic and Fluoride from Drinking Water in Chihuahua, Mexico
AbstractInorganic arsenic (iAs) and fluoride (F−) are naturally occurring drinking water contaminants. However, co-exposure to these contaminants and its effects on human health are understudied. The goal of this study was examined exposures to iAs and F− in Chihuahua, Mexico, where exposure to iAs in drinking water has been associated with adverse health effects. All 1119 eligible Chihuahua residents (>18 years) provided a sample of drinking water and spot urine samples. iAs and F− concentrations in water samples ranged from 0.1 to 419.8 µg As/L and from 0.05 to 11.8 mg F−/L. Urinary arsenic (U-tAs) and urinary F− (U-F−) levels ranged from 0.5 to 467.9 ng As/mL and from 0.1 to 14.4 µg F−/mL. A strong positive correlation was found between iAs and F− concentrations in drinking water (rs = 0.741). Similarly, U-tAs levels correlated positively with U-F− concentrations (rs = 0.633). These results show that Chihuahua residents exposed to high iAs concentrations in drinking water are also exposed to high levels of F−, raising questions about possible contribution of F− exposure to the adverse effects that have so far been attributed only to iAs exposure. Thus, investigation of possible interactions between iAs and F− exposures and its related health risks deserves immediate attention. View Full-Text
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González-Horta, C.; Ballinas-Casarrubias, L.; Sánchez-Ramírez, B.; Ishida, M.C.; Barrera-Hernández, A.; Gutiérrez-Torres, D.; Zacarias, O.L.; Saunders, R.J.; Drobná, Z.; Mendez, M.A.; García-Vargas, G.; Loomis, D.; Stýblo, M.; Del Razo, L.M. A Concurrent Exposure to Arsenic and Fluoride from Drinking Water in Chihuahua, Mexico. Int. J. Environ. Res. Public Health 2015, 12, 4587-4601.
González-Horta C, Ballinas-Casarrubias L, Sánchez-Ramírez B, Ishida MC, Barrera-Hernández A, Gutiérrez-Torres D, Zacarias OL, Saunders RJ, Drobná Z, Mendez MA, García-Vargas G, Loomis D, Stýblo M, Del Razo LM. A Concurrent Exposure to Arsenic and Fluoride from Drinking Water in Chihuahua, Mexico. International Journal of Environmental Research and Public Health. 2015; 12(5):4587-4601.Chicago/Turabian Style
González-Horta, Carmen; Ballinas-Casarrubias, Lourdes; Sánchez-Ramírez, Blanca; Ishida, María C.; Barrera-Hernández, Angel; Gutiérrez-Torres, Daniela; Zacarias, Olga L.; Saunders, R. J.; Drobná, Zuzana; Mendez, Michelle A.; García-Vargas, Gonzalo; Loomis, Dana; Stýblo, Miroslav; Del Razo, Luz M. 2015. "A Concurrent Exposure to Arsenic and Fluoride from Drinking Water in Chihuahua, Mexico." Int. J. Environ. Res. Public Health 12, no. 5: 4587-4601.