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Int. J. Environ. Res. Public Health 2015, 12(4), 4395-4405; doi:10.3390/ijerph120404395

Isolated Diastolic Hypertension Associated Risk Factors among Chinese in Anhui Province, China

1
School of Public Health, Wannan Medical College, Wuhu 241002, China
2
The Department of Pathology, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu 322000, China
3
School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, China
4
School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
*
Authors to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 2 March 2015 / Revised: 29 March 2015 / Accepted: 31 March 2015 / Published: 22 April 2015
View Full-Text   |   Download PDF [661 KB, uploaded 22 April 2015]

Abstract

Objective: To explore potential risk factors of isolated diastolic hypertension (IDH) among young and middle-aged Chinese. Methods: A community-based cross-sectional study was conducted among 338 subjects, aged 25 years and above, using random sampling technique. There were 68 cases of IDH, 46 cases of isolated systolic hypertension (ISH), 89 cases of systolic and diastolic hypertension (SDH), and 135 of subjects with normal blood pressure. Cases and controls were matched on sex by frequency matching. Demographic characteristics, blood pressure and other relevant information were collected. Results: Compared with controls, patients with IDH and ISH had significant higher level of triglyceride, high density lipoprotein, blood glucose and body mass index (BMI) (p < 0.05); while patients with SDH had significantly higher level of total cholesterol, triglyceride, glucose and BMI (p < 0.05). Linear mixed effects model showed that drinking tea, family history of hypertension (FHH), higher blood glucose, triglyceride and low density lipoprotein were related with elevated diastolic blood pressure (DBP) (p < 0.01); HFH, blood glucose, creatinine and BMI have positive effect on systolic blood pressure (SBP) (p < 0.05). Conclusions: Drinking tea, FHH, high levels of triglyceride, high density lipoprotein, blood glucose and BMI are associated with IDH among young and middle-aged Chinese. View Full-Text
Keywords: isolated diastolic hypertension; linear mixed model; case-control study isolated diastolic hypertension; linear mixed model; case-control study
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Wang, Y.; Xing, F.; Liu, R.; Liu, L.; Zhu, Y.; Wen, Y.; Sun, W.; Song, Z. Isolated Diastolic Hypertension Associated Risk Factors among Chinese in Anhui Province, China. Int. J. Environ. Res. Public Health 2015, 12, 4395-4405.

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