Next Article in Journal
Exposure to Air Ions in Indoor Environments: Experimental Study with Healthy Adults
Next Article in Special Issue
A Systematic Review and Meta-Regression Analysis of Lung Cancer Risk and Inorganic Arsenic in Drinking Water
Previous Article in Journal
Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease
Previous Article in Special Issue
Arsenic in Drinking Water, Transition Cell Cancer and Chronic Cystitis in Rural Bangladesh
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2015, 12(11), 14285-14300; doi:10.3390/ijerph121114285

Arsenic and Other Metals’ Presence in Biomarkers of Cambodians in Arsenic Contaminated Areas

1
Environmental Research Institute, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand
2
Center of Excellence on Hazardous Substance Management (HSM), Chulalongkorn University, Bangkok 10330, Thailand
3
Department of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan
4
Department of Environmental Engineering, College of Engineering, Dong-A University, 37 Nakdong-Daero 550 Beon-gil, Saha-gu, Busan 604-714, Korea
*
Author to whom correspondence should be addressed.
Academic Editors: Ravi Naidu and Mohammad Mahmudur Rahman
Received: 30 September 2015 / Revised: 30 October 2015 / Accepted: 4 November 2015 / Published: 10 November 2015
(This article belongs to the Special Issue Arsenic in Drinking Water: Current Perspectives and Future Directions)
View Full-Text   |   Download PDF [888 KB, uploaded 10 November 2015]   |  

Abstract

Chemical analyses of metal (Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Mo, Ba, and Pb) concentrations in hair, nails, and urine of Cambodians in arsenic-contaminated areas who consumed groundwater daily showed elevated levels in these biomarkers for most metals of toxicological interest. The levels of metals in biomarkers corresponded to their levels in groundwater, especially for As, whose concentrations exceeded the WHO guidelines for drinking water. About 75.6% of hair samples from the population in this study contained As levels higher than the normal level in unexposed individuals (1 mg·kg−1). Most of the population (83.3%) showed As urinary levels exceeding the normal (<50 ng·mg−1). These results indicate the possibility of arsenicosis symptoms in residents of the areas studied. Among the three biomarkers tested, hair has shown to be a reliable indicator of metal exposures. The levels of As (r2 = 0.633), Ba (r2 = 0.646), Fe (r2 = 0.595), and Mo (r2 = 0.555) in hair were strongly positively associated with the levels of those metals in groundwater. In addition, significant weak correlations (p < 0.01) were found between levels of exposure to As and As concentrations in both nails (r2 = 0.544) and urine (r2 = 0.243). View Full-Text
Keywords: arsenic; hair; nails; urine; biomarker; chronic exposure arsenic; hair; nails; urine; biomarker; chronic exposure
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chanpiwat, P.; Himeno, S.; Sthiannopkao, S. Arsenic and Other Metals’ Presence in Biomarkers of Cambodians in Arsenic Contaminated Areas. Int. J. Environ. Res. Public Health 2015, 12, 14285-14300.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top