Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata
AbstractA new sulfated sterol, phallusiasterol C (1), has been isolated from the Mediterranean ascidian Phallusia fumigata and its structure has been determined on the basis of extensive spectroscopic (mainly 2D NMR) analysis. The possible role in regulating the pregnane X receptor (PXR) activity of phallusiasterol C has been investigated; although the new sterol resulted inactive, this study adds more items to the knowledge of the structure-PXR regulating activity relationships in the case of sulfated steroids. View Full-Text
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Imperatore, C.; Senese, M.; Aiello, A.; Luciano, P.; Fiorucci, S.; D’Amore, C.; Carino, A.; Menna, M. Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata. Mar. Drugs 2016, 14, 117.
Imperatore C, Senese M, Aiello A, Luciano P, Fiorucci S, D’Amore C, Carino A, Menna M. Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata. Marine Drugs. 2016; 14(6):117.Chicago/Turabian Style
Imperatore, Concetta; Senese, Maria; Aiello, Anna; Luciano, Paolo; Fiorucci, Stefano; D’Amore, Claudio; Carino, Adriana; Menna, Marialuisa. 2016. "Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata." Mar. Drugs 14, no. 6: 117.
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