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Mar. Drugs 2016, 14(4), 81; doi:10.3390/md14040081

Antibacterial Derivatives of Marine Algae: An Overview of Pharmacological Mechanisms and Applications

School of Food Science and Environmental Health, College of Sciences and Health, Dublin Institute of Technology, Cathal Brugha Street, Dublin D01 HV58, Ireland
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Academic Editors: Tracy John Mincer and David C. Rowley
Received: 24 February 2016 / Revised: 13 April 2016 / Accepted: 15 April 2016 / Published: 22 April 2016
(This article belongs to the Special Issue Antibacterial Marine Pharmacology)
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Abstract

The marine environment is home to a taxonomically diverse ecosystem. Organisms such as algae, molluscs, sponges, corals, and tunicates have evolved to survive the high concentrations of infectious and surface-fouling bacteria that are indigenous to ocean waters. Both macroalgae (seaweeds) and microalgae (diatoms) contain pharmacologically active compounds such as phlorotannins, fatty acids, polysaccharides, peptides, and terpenes which combat bacterial invasion. The resistance of pathogenic bacteria to existing antibiotics has become a global epidemic. Marine algae derivatives have shown promise as candidates in novel, antibacterial drug discovery. The efficacy of these compounds, their mechanism of action, applications as antibiotics, disinfectants, and inhibitors of foodborne pathogenic and spoilage bacteria are reviewed in this article. View Full-Text
Keywords: marine antibacterial; seaweeds; micro-algae; nutraceuticals; antibiotic-resistance; food preservation; disinfectants; allelopathy marine antibacterial; seaweeds; micro-algae; nutraceuticals; antibiotic-resistance; food preservation; disinfectants; allelopathy
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Shannon, E.; Abu-Ghannam, N. Antibacterial Derivatives of Marine Algae: An Overview of Pharmacological Mechanisms and Applications. Mar. Drugs 2016, 14, 81.

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