Next Article in Journal
Extraction, Isolation, Structural Characterization and Anti-Tumor Properties of an Apigalacturonan-Rich Polysaccharide from the Sea Grass Zostera caespitosa Miki
Next Article in Special Issue
Dangerous Relations in the Arctic Marine Food Web: Interactions between Toxin Producing Pseudo-nitzschia Diatoms and Calanus Copepodites
Previous Article in Journal
Effect of Marine Collagen Peptides on Physiological and Neurobehavioral Development of Male Rats with Perinatal Asphyxia
Previous Article in Special Issue
The Effect of Dissolved Polyunsaturated Aldehydes on Microzooplankton Growth Rates in the Chesapeake Bay and Atlantic Coastal Waters
Article Menu

Export Article

Open AccessReview
Mar. Drugs 2015, 13(6), 3672-3709; doi:10.3390/md13063672

Low-Molecular-Weight Metabolites from Diatoms: Structures, Biological Roles and Biosynthesis

1
Laboratory of Chemistry of Marine Natural Products, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, Vladivostok 690022, Russia
2
Far Eastern Federal University, Sukhanova Str. 8, Vladivostok 690950, Russia
3
Laboratory of Ecology of the Shelf Communities, A.V. Zhirmunsky Institute of Marine Biology, FEB RAS, Vladivostok 690041, Russia
*
Author to whom correspondence should be addressed.
Academic Editor: Véronique Martin-Jézéquel
Received: 12 February 2015 / Revised: 5 May 2015 / Accepted: 14 May 2015 / Published: 9 June 2015
(This article belongs to the Special Issue Metabolites in Diatoms)

Abstract

Diatoms are abundant and important biological components of the marine environment that biosynthesize diverse natural products. These microalgae are rich in various lipids, carotenoids, sterols and isoprenoids, some of them containing toxins and other metabolites. Several groups of diatom natural products have attracted great interest due to their potential practical application as energy sources (biofuel), valuable food constituents, and prospective materials for nanotechnology. In addition, hydrocarbons, which are used in climate reconstruction, polyamines which participate in biomineralization, new apoptotic agents against tumor cells, attractants and deterrents that regulate the biochemical communications between marine species in seawaters have also been isolated from diatoms. However, chemical studies on these microalgae are complicated by difficulties, connected with obtaining their biomass, and the influence of nutrients and contaminators in their environment as well as by seasonal and climatic factors on the biosynthesis of the corresponding natural products. Overall, the number of chemically studied diatoms is lower than that of other algae, but further studies, particularly those connected with improvements in the isolation and structure elucidation technique as well as the genomics of diatoms, promise both to increase the number of studied species with isolated biologically active natural products and to provide a clearer perception of their biosynthesis. View Full-Text
Keywords: diatoms; lipids; oxylipins; sterols; isoprenoid hydrocarbons; pigments; domoic acid; miscellaneous diatoms; lipids; oxylipins; sterols; isoprenoid hydrocarbons; pigments; domoic acid; miscellaneous
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Stonik, V.; Stonik, I. Low-Molecular-Weight Metabolites from Diatoms: Structures, Biological Roles and Biosynthesis. Mar. Drugs 2015, 13, 3672-3709.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top