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Mar. Drugs 2014, 12(3), 1580-1622; doi:10.3390/md12031580
Review

Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges

 and *
Received: 30 December 2013; in revised form: 24 January 2014 / Accepted: 25 February 2014 / Published: 18 March 2014
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Abstract: Sponges corresponding to the Jaspidae family have proved to be a prolific source of bioactive natural products. Among these, the bengamides and the bengazoles stand out by virtue of their unprecedented molecular architectures and impressive biological profiles, including antitumor, antibiotic and anthelmintic properties. As a consequence, intense research activity has been devoted to these compounds from both chemical and biological standpoints. This review describes in detail the research into these classes of natural products and the benefits they offer in chemistry and biology.
Keywords: bengamides; bengazoles; antitumor; analogues; total synthesis bengamides; bengazoles; antitumor; analogues; total synthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

García-Ruiz, C.; Sarabia, F. Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges. Mar. Drugs 2014, 12, 1580-1622.

AMA Style

García-Ruiz C, Sarabia F. Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges. Marine Drugs. 2014; 12(3):1580-1622.

Chicago/Turabian Style

García-Ruiz, Cristina; Sarabia, Francisco. 2014. "Chemistry and Biology of Bengamides and Bengazoles, Bioactive Natural Products from Jaspis Sponges." Mar. Drugs 12, no. 3: 1580-1622.


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