Next Article in Journal
Polyoxygenated Steroids from the Octocoral Leptogorgia punicea and in Vitro Evaluation of Their Cytotoxic Activity
Next Article in Special Issue
New Meroterpenoids from the Endophytic Fungus Aspergillus flavipes AIL8 Derived from the Mangrove Plant Acanthus ilicifolius
Previous Article in Journal
Chromomycin A2 Induces Autophagy in Melanoma Cells
Previous Article in Special Issue
Oxygenated Eremophilane- and Neolemnane-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis
Article Menu

Export Article

Open AccessCommunication
Mar. Drugs 2014, 12(12), 5856-5863; doi:10.3390/md12125856

Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies

1
Department of Applied Chemistry, National Pingtung University, Pingtung 900, Taiwan
2
Department of Marine Biotechnology and Resources, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
3
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
4
Graduate Institute of Natural Products, School of Traditional Medicine, College of Medicine, and Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Taoyuan 333, Taiwan
5
Department of Cosmetic Science and Research Center for Industry of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan
6
Department of Sport, Health and Leisure, Cheng Shiu University, Kaohsiung 833, Taiwan
7
Department of Pharmacy, Tajen University, Pingtung 907, Taiwan
8
School of Pharmacy, College of Pharmacy, China Medical University, Taichung 404, Taiwan
9
Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 404, Taiwan
10
Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan
11
Graduate Institute of Marine Biology, Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
12
Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 9 September 2014 / Revised: 4 November 2014 / Accepted: 21 November 2014 / Published: 4 December 2014
(This article belongs to the Special Issue Terpenoids of Marine Origin)
View Full-Text   |   Download PDF [410 KB, uploaded 24 February 2015]   |  

Abstract

A novel sesquiterpenoid, rumphellaoic acid A (1), was isolated from the gorgonian coral Rumphella antipathies, and was found to possess a carbon skeleton that was obtained for the first time from a natural sources. The structure of 1 was elucidated by spectroscopic methods and this compound and was found to exert a moderate inhibitory effect on the release of elastase by human neutrophils. View Full-Text
Keywords: Rumphella antipathies; gorgonian; rumphellaoic acid; sesquiterpenoid; elastase Rumphella antipathies; gorgonian; rumphellaoic acid; sesquiterpenoid; elastase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chung, H.-M.; Wang, W.-H.; Hwang, T.-L.; Fang, L.-S.; Wen, Z.-H.; Chen, J.-J.; Wu, Y.-C.; Sung, P.-J. Rumphellaoic Acid A, a Novel Sesquiterpenoid from the Formosan Gorgonian Coral Rumphella antipathies. Mar. Drugs 2014, 12, 5856-5863.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top