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Mar. Drugs 2013, 11(11), 4407-4418; doi:10.3390/md11114407
Article

New Constituents from the Korean Sponge Plakortis simplex

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Received: 10 July 2013 / Revised: 30 September 2013 / Accepted: 14 October 2013 / Published: 5 November 2013
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Abstract

Six new cyclic peroxides (16) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 16 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.
Keywords: Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Oh, J.S.; Hwang, B.S.; Kang, O.-H.; Kwon, D.-Y.; Rho, J.-R. New Constituents from the Korean Sponge Plakortis simplex. Mar. Drugs 2013, 11, 4407-4418.

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