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New Constituents from the Korean Sponge Plakortis simplex
Department of Oceanography, Kunsan National University, Jeonbuk 573-701, Korea
College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Institute of Biotechnology, Wonkwang University, Jeonbuk 570-749, Korea
* Author to whom correspondence should be addressed.
Received: 10 July 2013; in revised form: 30 September 2013 / Accepted: 14 October 2013 / Published: 5 November 2013
Abstract: Six new cyclic peroxides (1–6) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 1–6 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.
Keywords: Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR
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Oh, J.S.; Hwang, B.S.; Kang, O.-H.; Kwon, D.-Y.; Rho, J.-R. New Constituents from the Korean Sponge Plakortis simplex. Mar. Drugs 2013, 11, 4407-4418.
Oh JS, Hwang BS, Kang O-H, Kwon D-Y, Rho J-R. New Constituents from the Korean Sponge Plakortis simplex. Marine Drugs. 2013; 11(11):4407-4418.
Oh, Jung S.; Hwang, Buyng S.; Kang, Ok-Hwa; Kwon, Dong-Yeul; Rho, Jung-Rae. 2013. "New Constituents from the Korean Sponge Plakortis simplex." Mar. Drugs 11, no. 11: 4407-4418.