Next Article in Journal
Crambescidin-816 Acts as a Fungicidal with More Potency than Crambescidin-800 and -830, Inducing Cell Cycle Arrest, Increased Cell Size and Apoptosis in Saccharomyces cerevisiae
Previous Article in Journal
Antiproliferative Activity of Cyanophora paradoxa Pigments in Melanoma, Breast and Lung Cancer Cells
Mar. Drugs 2013, 11(11), 4407-4418; doi:10.3390/md11114407
Article

New Constituents from the Korean Sponge Plakortis simplex

1
, 1
, 2
, 2
 and 1,*
1 Department of Oceanography, Kunsan National University, Jeonbuk 573-701, Korea 2 College of Pharmacy and Wonkwang-Oriental Medicines Research Institute, Institute of Biotechnology, Wonkwang University, Jeonbuk 570-749, Korea
* Author to whom correspondence should be addressed.
Received: 10 July 2013 / Revised: 30 September 2013 / Accepted: 14 October 2013 / Published: 5 November 2013
View Full-Text   |   Download PDF [502 KB, uploaded 24 February 2015]   |   Browse Figures

Abstract

Six new cyclic peroxides (16) were isolated from the Korean sponge Plakortis simplex, along with two new alkylpyridinium alkaloids (7 and 8). The structures of these compounds were completely determined by a combination of NMR analysis and chemical reactions. Compounds 16 exhibited cytotoxic/antifungal activities against RAW264.7 cells and Candida albicans.
Keywords: Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR Plakortis simplex; cyclic peroxide; cyclic peroxyketal; pyridinium; NMR
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Oh, J.S.; Hwang, B.S.; Kang, O.-H.; Kwon, D.-Y.; Rho, J.-R. New Constituents from the Korean Sponge Plakortis simplex. Mar. Drugs 2013, 11, 4407-4418.

View more citation formats

Supplement

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert