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Mar. Drugs 2013, 11(10), 3601-3616; doi:10.3390/md11103601
Review

Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South China Sea

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1 Department of Neurosurgery and Pituitary Tumour Center, the First Affiliated Hospital of Sun Yat-sen University, No. 74, Zhongshan Road 2, Guangzhou 510080, China 2 Department of Histology and Embryology, Medical school of Sun Yat-sen University, No. 74, Zhongshan Road 2, Guangzhou 510080, China 3 Key Laboratory of Functional Molecules from Marine Microorganisms, Department of Education of Guangdong Province, Sun Yat-sen University, No. 74, Zhongshan Road 2, Guangzhou 510080, China
* Authors to whom correspondence should be addressed.
Received: 1 August 2013 / Revised: 21 August 2013 / Accepted: 3 September 2013 / Published: 30 September 2013
(This article belongs to the Special Issue Cytogenetic and Molecular Effects of Marine Compounds)
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Abstract

Many metabolites with novel structures and biological activities have been isolated from the mangrove fungi in the South China Sea, such as anthracenediones, xyloketals, sesquiterpenoids, chromones, lactones, coumarins and isocoumarin derivatives, xanthones, and peroxides. Some compounds have anticancer, antibacterial, antifungal and antiviral properties, but the biosynthesis of these compounds is still limited. This review summarizes the advances in the study of secondary metabolites from the mangrove-derived fungi in the South China Sea, and their biological activities reported between 2008 and mid-2013.
Keywords: marine metabolites; fungus; mangrove; biological activity; south China sea marine metabolites; fungus; mangrove; biological activity; south China sea
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, X.; Mao, Z.-G.; Song, B.-B.; Chen, C.-H.; Xiao, W.-W.; Hu, B.; Wang, J.-W.; Jiang, X.-B.; Zhu, Y.-H.; Wang, H.-J. Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South China Sea. Mar. Drugs 2013, 11, 3601-3616.

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