Pharmaceuticals 2010, 3(1), 10-18; doi:10.3390/ph3010010
Review

Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update

Mario Sánchez-Borges 1,* email, Fernan Caballero-Fonseca 1 email, Arnaldo Capriles-Hulett 1 email and Luis González-Aveledo 2 email
1 Allergy and Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela 2 Dermatology Service, Centro Médico de Caracas, Caracas, Venezuela
* Author to whom correspondence should be addressed.
Received: 17 December 2009 / Accepted: 30 December 2009 / Published: 5 January 2010
(This article belongs to the Special Issue Non-Steroidal Anti-Inflammatory Drugs)
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Abstract: After beta lactam antibiotics, hypersensitivity reactions to nonsteroidal antiinflammatory drugs are the second cause of hypersensitivity to drugs. Acute manifestations affect the respiratory tract (aspirin exacerbated respiratory disease), the skin (urticaria and angioedema), or are generalized (anaphylaxis). Correct diagnosis and treatment in order to prevent unnecessary morbidity and the potential risk of death from these severe reactions, and to provide proper medical advice on future drug use frequently requires the participation of allergology specialists familiar with these clinical conditions.
Keywords: asthma; anaphylaxis; drug reactions; non steroidal anti-inflammatory drugs (NSAIDs); urticaria and angioedema

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MDPI and ACS Style

Sánchez-Borges, M.; Caballero-Fonseca, F.; Capriles-Hulett, A.; González-Aveledo, L. Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update. Pharmaceuticals 2010, 3, 10-18.

AMA Style

Sánchez-Borges M, Caballero-Fonseca F, Capriles-Hulett A, González-Aveledo L. Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update. Pharmaceuticals. 2010; 3(1):10-18.

Chicago/Turabian Style

Sánchez-Borges, Mario; Caballero-Fonseca, Fernan; Capriles-Hulett, Arnaldo; González-Aveledo, Luis. 2010. "Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update." Pharmaceuticals 3, no. 1: 10-18.

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