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Sensors 2009, 9(9), 7111-7131; doi:10.3390/s90907111
Review

Ion-Sensitive Field-Effect Transistor for Biological Sensing

1
, 1,2
 and 1,*
Received: 4 August 2009; in revised form: 27 August 2009 / Accepted: 31 August 2009 / Published: 7 September 2009
(This article belongs to the Special Issue ISFET Sensors)
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Abstract: In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells.
Keywords: ISFET; ion-sensitive field-effect transistor; biosensor; biomolecules ISFET; ion-sensitive field-effect transistor; biosensor; biomolecules
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Lee, C.-S.; Kim, S.K.; Kim, M. Ion-Sensitive Field-Effect Transistor for Biological Sensing. Sensors 2009, 9, 7111-7131.

AMA Style

Lee C-S, Kim SK, Kim M. Ion-Sensitive Field-Effect Transistor for Biological Sensing. Sensors. 2009; 9(9):7111-7131.

Chicago/Turabian Style

Lee, Chang-Soo; Kim, Sang K.; Kim, Moonil. 2009. "Ion-Sensitive Field-Effect Transistor for Biological Sensing." Sensors 9, no. 9: 7111-7131.


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