Sensors 2007, 7(8), 1643-1654; doi:10.3390/s7081643
Article

Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips

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Received: 11 June 2007; Accepted: 24 August 2007 / Published: 27 August 2007
(This article belongs to the Special Issue Modeling, Testing and Reliability Issues in MEMS Engineering)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Recently, the polymeric micro-fluidic biochip, often called LOC (lab-on-a-chip), has been focused as a cheap, rapid and simplified method to replace the existing biochemical laboratory works. It becomes possible to form miniaturized lab functionalities on a chip with the development of MEMS technologies. The micro-fluidic chips contain many micro-channels for the flow of sample and reagents, mixing, and detection tasks. Typical substrate materials for the chip are glass and polymers. Typical techniques for micro-fluidic chip fabrication are utilizing various micro pattern forming methods, such as wet-etching, micro-contact printing, and hot-embossing, micro injection molding, LIGA, and micro powder blasting processes, etc. In this study, to establish the basis of the micro pattern fabrication and mass production of polymeric micro-fluidic chips using injection molding process, micro machining method was applied to form micro-channels on the LOC molds. In the research, a series of machining experiments using micro end-mills were performed to determine optimum machining conditions to improve surface roughness and shape accuracy of designed simplified micro-channels. Obtained conditions were used to machine required mold inserts for micro-channels using micro end-mills. Test injection processes using machined molds and COC polymer were performed, and then the results were investigated.
Keywords: Biochip; lab-on-a-chip; micro machining; injection molding; mold inserts.
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MDPI and ACS Style

Jung, W.-C.; Heo, Y.-M.; Yoon, G.-S.; Shin, K.-H.; Chang, S.-H.; Kim, G.-H.; Cho, M.-W. Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips. Sensors 2007, 7, 1643-1654.

AMA Style

Jung W-C, Heo Y-M, Yoon G-S, Shin K-H, Chang S-H, Kim G-H, Cho M-W. Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips. Sensors. 2007; 7(8):1643-1654.

Chicago/Turabian Style

Jung, Woo-Chul; Heo, Young-Moo; Yoon, Gil-Sang; Shin, Kwang-Ho; Chang, Sung-Ho; Kim, Gun-Hee; Cho, Myeong-Woo. 2007. "Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips." Sensors 7, no. 8: 1643-1654.

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