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Electrochemical DNA Sensors for Detection of DNA Damage
Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal
* Author to whom correspondence should be addressed.
Received: 3 February 2005 / Accepted: 14 March 2005 / Published: 14 November 2005
Abstract: Electrochemical devices have received particular attention due to their rapiddetection and great sensitivity for the evaluation of DNA-hazard compounds interactionmechanisms. Several types of bioanalytical method use nucleic acids probes to detect DNAdamage. This article reviews current directions and strategies in the development andapplications of electrochemical DNA sensors for the detection of DNA damage.
Keywords: DNA-electrochemical biosensor; DNA damage; damage to DNA bases; oxidative stress; biomarker of DNA damage; 8-oxo-7; 8-dihydroxguanine (8-oxoGua); 8-oxo-7; 8-dihydro-2’-deoxyguanosine (8-oxodGuo).
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Cite This Article
MDPI and ACS Style
Diculescu, V.C.; Paquim, A.-M.C.; Brett, A.M.O. Electrochemical DNA Sensors for Detection of DNA Damage. Sensors 2005, 5, 377-393.
Diculescu VC, Paquim A-MC, Brett AMO. Electrochemical DNA Sensors for Detection of DNA Damage. Sensors. 2005; 5(6):377-393.
Diculescu, Victor C.; Paquim, Ana-Maria C.; Brett, Ana Maria O. 2005. "Electrochemical DNA Sensors for Detection of DNA Damage." Sensors 5, no. 6: 377-393.