Sensors 2005, 5(6), 377-393; doi:10.3390/s5060377
Review

Electrochemical DNA Sensors for Detection of DNA Damage

Victor Constantin Diculescu, Ana-Maria Chiorcea Paquim and Ana Maria Oliveira Brett* email
Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535 Coimbra, Portugal
* Author to whom correspondence should be addressed.
Received: 3 February 2005 / Accepted: 14 March 2005 / Published: 14 November 2005
(This article belongs to the Special Issue DNA Based Sensors)
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Abstract: Electrochemical devices have received particular attention due to their rapiddetection and great sensitivity for the evaluation of DNA-hazard compounds interactionmechanisms. Several types of bioanalytical method use nucleic acids probes to detect DNAdamage. This article reviews current directions and strategies in the development andapplications of electrochemical DNA sensors for the detection of DNA damage.
Keywords: DNA-electrochemical biosensor; DNA damage; damage to DNA bases; oxidative stress; biomarker of DNA damage; 8-oxo-7; 8-dihydroxguanine (8-oxoGua); 8-oxo-7; 8-dihydro-2’-deoxyguanosine (8-oxodGuo).

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Cite This Article

MDPI and ACS Style

Diculescu, V.C.; Paquim, A.-M.C.; Brett, A.M.O. Electrochemical DNA Sensors for Detection of DNA Damage. Sensors 2005, 5, 377-393.

AMA Style

Diculescu VC, Paquim A-MC, Brett AMO. Electrochemical DNA Sensors for Detection of DNA Damage. Sensors. 2005; 5(6):377-393.

Chicago/Turabian Style

Diculescu, Victor C.; Paquim, Ana-Maria C.; Brett, Ana Maria O. 2005. "Electrochemical DNA Sensors for Detection of DNA Damage." Sensors 5, no. 6: 377-393.

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