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Sensors 2003, 3(6), 160-165; doi:10.3390/s30600160

Comparison of Urea Determination in Biological Samples by EnFETs Based on pH and pNH4 Detection

Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, ul. Trojdena 4, 02-109 Warsaw, Poland
Author to whom correspondence should be addressed.
Received: 16 April 2003 / Accepted: 16 June 2003 / Published: 29 June 2003
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In this paper urea biosensors based on detection of pH and ammonium ions are presented. As transducers pH-sensitive ion-selective field effect transistors (ISFETs) and chemically modified FETs (ChemFETs) snsitive to ammonium ions were used.Results concerning urea determination by the bisensors in blood plasma and in dialysate show that the biosensors can be applied for urea monitoring in the effluent dialysate. However in the case of pNH4 based EnFETs a special pre-treatment (dilution with tris/HCl buffer) of the samples is necessary.
Keywords: Urea detection; biosensors; EnFET; enzyme immobilisation Urea detection; biosensors; EnFET; enzyme immobilisation
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Bijanowska, D.G.; Dawgul, M.; Torbicz, W. Comparison of Urea Determination in Biological Samples by EnFETs Based on pH and pNH4 Detection. Sensors 2003, 3, 160-165.

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