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Sensors 2017, 17(12), 2797; https://doi.org/10.3390/s17122797

A Low-Cost and Portable Dual-Channel Fiber Optic Surface Plasmon Resonance System

School of Physics and Optoelectronic Technology, Dalian University of Technology, 2 Linggong Road, Ganjingzi District, Dalian 116024, China
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Received: 10 November 2017 / Revised: 24 November 2017 / Accepted: 1 December 2017 / Published: 4 December 2017
(This article belongs to the Special Issue Surface Plasmon Resonance Sensing)
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Abstract

A miniaturization and integration dual-channel fiber optic surface plasmon resonance (SPR) system was proposed and demonstrated in this paper. We used a yellow light-emitting diode (LED, peak wavelength 595 nm) and built-in web camera as a light source and detector, respectively. Except for the detection channel, one of the sensors was used as a reference channel to compensate nonspecific binding and physical absorption. We packaged the LED and surface plasmon resonance (SPR) sensors together, which are flexible enough to be applied to mobile devices as a compact and portable system. Experimental results show that the normalized intensity shift and refractive index (RI) of the sample have a good linear relationship in the RI range from 1.328 to 1.348. We used this sensor to monitor the reversible, specific interaction between lectin concanavalin A (Con A) and glycoprotein ribonuclease B (RNase B), which demonstrate its capabilities of specific identification and biochemical samples concentration detection. This sensor system has potential applications in various fields, such as medical diagnosis, public health, food safety, and environment monitoring. View Full-Text
Keywords: Low cost and portable; fiber optic surface plasmon resonance; dual-channel; biosensor Low cost and portable; fiber optic surface plasmon resonance; dual-channel; biosensor
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Liu, Q.; Liu, Y.; Chen, S.; Wang, F.; Peng, W. A Low-Cost and Portable Dual-Channel Fiber Optic Surface Plasmon Resonance System. Sensors 2017, 17, 2797.

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