A Sensitive and Stable Surface Plasmon Resonance Sensor Based on Monolayer Protected Silver Film
AbstractIn this paper, we present a stable silver-based surface plasmon resonance (SPR) sensor using a self-assembled monolayer (SAM) as a protection layer and investigated its efficiency in water and 0.01 M phosphate buffered saline (PBS). By simulation, silver-based SPR sensor has a better performance in field enhancement and penetration depth than that of a gold-based SPR sensor, which are 5 and 1.4 times, respectively. To overcome the instability of the bare silver film and investigate the efficiency of the protected layer, the SAM of 11-mercapto-1-undecanol (MUD) was used as a protection layer. Stability experiment results show that the protected silver film exhibited excellent stability either in pure water or 0.01 M PBS buffer. The sensitivity of the silver-based SPR sensor was calculated to be 127.26 deg/RIU (refractive index unit), measured with different concentrations of NaCl solutions. Further, a very high refractive resolution for the silver-based SPR sensor was found to be 2.207 × 10−7 RIU, which reaches the theoretical limit in the wavelength of 632.8 nm for a SPR sensor reported in the literature. Using a mixed SAM of 16-mercaptohexadecanoic acid (MHDA) and a MUD layer with a ratio of 1:10, this immunosensor for the rabbit immunoglobulin G (IgG) molecule with a limit of detection as low as 22.516 ng/mL was achieved. View Full-Text
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Wang, G.; Wang, C.; Yang, R.; Liu, W.; Sun, S. A Sensitive and Stable Surface Plasmon Resonance Sensor Based on Monolayer Protected Silver Film. Sensors 2017, 17, 2777.
Wang G, Wang C, Yang R, Liu W, Sun S. A Sensitive and Stable Surface Plasmon Resonance Sensor Based on Monolayer Protected Silver Film. Sensors. 2017; 17(12):2777.Chicago/Turabian Style
Wang, Guiqiang; Wang, Chunnan; Yang, Rui; Liu, Wenlan; Sun, Shuqing. 2017. "A Sensitive and Stable Surface Plasmon Resonance Sensor Based on Monolayer Protected Silver Film." Sensors 17, no. 12: 2777.
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