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Sensors 2017, 17(10), 2375; doi:10.3390/s17102375

Disease-Related Detection with Electrochemical Biosensors: A Review

1
Chongqing Key Laboratory of Non-linear Circuit and Intelligent Information Processing, College of Electronic and Information Engineering, Southwest University, Chongqing 400715, China
2
Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University) Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China
3
CET-College of Engineering and Technology, Southwest University, Chongqing 400715, China
*
Author to whom correspondence should be addressed.
Received: 12 September 2017 / Revised: 10 October 2017 / Accepted: 14 October 2017 / Published: 17 October 2017
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Abstract

Rapid diagnosis of diseases at their initial stage is critical for effective clinical outcomes and promotes general public health. Classical in vitro diagnostics require centralized laboratories, tedious work and large, expensive devices. In recent years, numerous electrochemical biosensors have been developed and proposed for detection of various diseases based on specific biomarkers taking advantage of their features, including sensitivity, selectivity, low cost and rapid response. This article reviews research trends in disease-related detection with electrochemical biosensors. Focus has been placed on the immobilization mechanism of electrochemical biosensors, and the techniques and materials used for the fabrication of biosensors are introduced in details. Various biomolecules used for different diseases have been listed. Besides, the advances and challenges of using electrochemical biosensors for disease-related applications are discussed. View Full-Text
Keywords: electrochemical biosensor; disease detection; biomolecules electrochemical biosensor; disease detection; biomolecules
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Huang, Y.; Xu, J.; Liu, J.; Wang, X.; Chen, B. Disease-Related Detection with Electrochemical Biosensors: A Review. Sensors 2017, 17, 2375.

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