Next Article in Journal
Real-Time QoS Routing Protocols in Wireless Multimedia Sensor Networks: Study and Analysis
Previous Article in Journal
A New Reassigned Spectrogram Method in Interference Detection for GNSS Receivers
Article Menu

Export Article

Open AccessArticle
Sensors 2015, 15(9), 22192-22208; doi:10.3390/s150922192

Simulations of Interdigitated Electrode Interactions with Gold Nanoparticles for Impedance-Based Biosensing Applications

1
Electrical and Computer Engineering Department, University of Alberta, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada
2
Department of Computing Science, 2-21 Athabasca Hall, University of Alberta, Edmonton, AB T6G 2E8, Canada
3
National Research Council/National Institute for Nanotechnology, 11421 Saskatchewan Dr NW, Edmonton, AB T6G 2M9, Canada
*
Author to whom correspondence should be addressed.
Academic Editor: Nicole Jaffrezic-Renault
Received: 15 July 2015 / Revised: 13 August 2015 / Accepted: 21 August 2015 / Published: 2 September 2015
(This article belongs to the Section Biosensors)
View Full-Text   |   Download PDF [2662 KB, uploaded 2 September 2015]   |  

Abstract

In this paper, we describe a point-of-care biosensor design. The uniqueness of our design is in its capability for detecting a wide variety of target biomolecules and the simplicity of nanoparticle enhanced electrical detection. The electrical properties of interdigitated electrodes (IDEs) and the mechanism for gold nanoparticle-enhanced impedance-based biosensor systems based on these electrodes are simulated using COMSOL Multiphysics software. Understanding these properties and how they can be affected is vital in designing effective biosensor devices. Simulations were used to show electrical screening develop over time for IDEs in a salt solution, as well as the electric field between individual digits of electrodes. Using these simulations, it was observed that gold nanoparticles bound closely to IDEs can lower the electric field magnitude between the digits of the electrode. The simulations are also shown to be a useful design tool in optimizing sensor function. Various different conditions, such as electrode dimensions and background ion concentrations, are shown to have a significant impact on the simulations. View Full-Text
Keywords: COMSOL; biosensor; gold nanoparticles; interdigitated electrodes COMSOL; biosensor; gold nanoparticles; interdigitated electrodes
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

MacKay, S.; Hermansen, P.; Wishart, D.; Chen, J. Simulations of Interdigitated Electrode Interactions with Gold Nanoparticles for Impedance-Based Biosensing Applications. Sensors 2015, 15, 22192-22208.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top