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Sensors 2015, 15(6), 12205-12217; doi:10.3390/s150612205

Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles

State Key Laboratory of Chemical Engineering, Tianjin Key Laboratory of Membrane Science and Desalination Technology, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China
Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, China
School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China
Authors to whom correspondence should be addressed.
Academic Editor: W. Rudolf Seitz
Received: 16 April 2015 / Revised: 11 May 2015 / Accepted: 18 May 2015 / Published: 26 May 2015
(This article belongs to the Special Issue Micro-Optical Sensors)
View Full-Text   |   Download PDF [1231 KB, uploaded 26 May 2015]   |  


In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing area and the coating time of the Ag NPs. A sensing length of 1.5 cm and a 1-h coating time proved to be suitable conditions to produce highly sensitive sensors for biosensing. The optimized sensor has a high refractive index sensitivity of 387 nm/RIU, which is much higher than that of other reported individual silver nanoparticles in solutions. Moreover, the sensor was further modified with antigen to act as a biosensor. Distinctive wavelength shifts were found after each surface modification step. In addition, the reflective LSPR optical fiber sensor has high reproducibility and stability. View Full-Text
Keywords: localized surface plasmon resonance; optical fiber; silver nanoparticles; biosensors localized surface plasmon resonance; optical fiber; silver nanoparticles; biosensors

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Chen, J.; Shi, S.; Su, R.; Qi, W.; Huang, R.; Wang, M.; Wang, L.; He, Z. Optimization and Application of Reflective LSPR Optical Fiber Biosensors Based on Silver Nanoparticles. Sensors 2015, 15, 12205-12217.

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