Next Article in Journal
Enhanced Sensitive Love Wave Surface Acoustic Wave Sensor Designed for Immunoassay Formats
Next Article in Special Issue
Localized Surface Plasmon Resonance Biosensing: Current Challenges and Approaches
Previous Article in Journal
Towards a Dynamic Clamp for Neurochemical Modalities
Previous Article in Special Issue
A New Z-axis Resonant Micro-Accelerometer Based on Electrostatic Stiffness
Article Menu

Export Article

Open AccessReview
Sensors 2015, 15(5), 10481-10510; doi:10.3390/s150510481

Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications

1,2,†
,
1,2,†
,
3,* and 1,2,4,*
1
BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 305-806, Korea
2
Department of Nanobiotechnology, Korea University of Science and Technology (UST), Daejeon 305-350, Korea
3
Department of Biological Sciences, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 689-798, Korea
4
Department of Pathobiology, College of Veterinary Medicine Nursing & Allied Health (CVMNAH), Tuskegee University, Tuskegee, AL 36088, USA
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Academic Editor: Yeshaiahu Fainman
Received: 12 March 2015 / Revised: 24 April 2015 / Accepted: 28 April 2015 / Published: 5 May 2015
(This article belongs to the Special Issue Resonant Sensors and Sensor Fusion)
View Full-Text   |   Download PDF [3192 KB, uploaded 5 May 2015]   |  

Abstract

Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review. View Full-Text
Keywords: surface plasmon resonance; SPR; biosensor; SPR imaging; applications surface plasmon resonance; SPR; biosensor; SPR imaging; applications
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Nguyen, H.H.; Park, J.; Kang, S.; Kim, M. Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications. Sensors 2015, 15, 10481-10510.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top