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Sensors 2015, 15(5), 10511-10525; doi:10.3390/s150510511

Enhanced Sensitive Love Wave Surface Acoustic Wave Sensor Designed for Immunoassay Formats

1
LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania
2
Department of Analytical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania
3
National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Blvd., RO-077125 Magurele, Romania
*
Author to whom correspondence should be addressed.
Academic Editor: Gerhard Lindner
Received: 14 March 2015 / Revised: 16 April 2015 / Accepted: 23 April 2015 / Published: 5 May 2015
(This article belongs to the Special Issue Acoustic Waveguide Sensors)
View Full-Text   |   Download PDF [1295 KB, uploaded 5 May 2015]   |  

Abstract

We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to other surface plasmon resonance bioassays having the advantage of requiring reduced time analysis. The fabricated LW-SAW sensor supports the detection of the target in the nanomolar range, and can be ultimately incorporated in portable devices, suitable for point-of-care testing (POCT) applications. View Full-Text
Keywords: surface acoustic wave; surface plasmon resonance; aflatoxin B1; immunoassay surface acoustic wave; surface plasmon resonance; aflatoxin B1; immunoassay
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Puiu, M.; Gurban, A.-M.; Rotariu, L.; Brajnicov, S.; Viespe, C.; Bala, C. Enhanced Sensitive Love Wave Surface Acoustic Wave Sensor Designed for Immunoassay Formats. Sensors 2015, 15, 10511-10525.

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