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Sensors 2014, 14(10), 18982-18992; doi:10.3390/s141018982

Chemoresistive Gas Sensors for the Detection of Colorectal Cancer Biomarkers

1,2,†,* , 1,2,†
,
1,†
,
1,3,†
,
1,2,3,†
,
1,†
and
1,2,†
1
Department of Physics and Earth Science, University of Ferrara, Via Saragat 1/c, Ferrara 44122, Italy
2
CNR-INO—Istituto Nazionale di Ottica, Largo Enrico Fermi 6, Firenze 50124, Italy
3
MIST E-R s.c.r.l., Via P. Gobetti 101, Bologna 40129, Italy
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 28 August 2014 / Revised: 24 September 2014 / Accepted: 25 September 2014 / Published: 13 October 2014
(This article belongs to the Section Chemical Sensors)
View Full-Text   |   Download PDF [1931 KB, uploaded 13 October 2014]   |  

Abstract

Numerous medical studies show that tumor growth is accompanied by protein changes that may lead to the peroxidation of the cell membrane with consequent emission of volatile organic compounds (VOCs) by breath or intestinal gases that should be seen as biomarkers for colorectal cancer (CRC). The analysis of VOCs represents a non-invasive and potentially inexpensive preliminary screening technique. An array of chemoresistive gas sensors based on screen-printed metal oxide semiconducting films has been selected to discriminate gases of oncological interest, e.g., 1-iodononane and benzene, widely assumed to be biomarkers of colorectal cancer, from those of interference in the gut, such as methane and nitric oxide. View Full-Text
Keywords: gas; sensors; nanotechnology; semiconductors; metal oxides; colorectal cancer; VOC; 1-iodo-nonane gas; sensors; nanotechnology; semiconductors; metal oxides; colorectal cancer; VOC; 1-iodo-nonane
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Malagù, C.; Fabbri, B.; Gherardi, S.; Giberti, A.; Guidi, V.; Landini, N.; Zonta, G. Chemoresistive Gas Sensors for the Detection of Colorectal Cancer Biomarkers. Sensors 2014, 14, 18982-18992.

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