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Sensors 2014, 14(10), 17981-18008; doi:10.3390/s141017981

Microelectronics-Based Biosensors Dedicated to the Detection of Neurotransmitters: A Review

Polystim Neurotechnologies Laboratory, Electrical Engineering Department, Polytechnique Montreal, Montreal, QC H3T1J4, Canada
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Received: 11 July 2014 / Revised: 28 August 2014 / Accepted: 9 September 2014 / Published: 26 September 2014
(This article belongs to the Special Issue Implantable Sensors)
View Full-Text   |   Download PDF [3314 KB, uploaded 26 September 2014]   |  

Abstract

Dysregulation of neurotransmitters (NTs) in the human body are related to diseases such as Parkinson’s and Alzheimer’s. The mechanisms of several neurological disorders, such as epilepsy, have been linked to NTs. Because the number of diagnosed cases is increasing, the diagnosis and treatment of such diseases are important. To detect biomolecules including NTs, microtechnology, micro and nanoelectronics have become popular in the form of the miniaturization of medical and clinical devices. They offer high-performance features in terms of sensitivity, as well as low-background noise. In this paper, we review various devices and circuit techniques used for monitoring NTs in vitro and in vivo and compare various methods described in recent publications. View Full-Text
Keywords: microtechnology; microsystems; microelectronics; biosensors; chemical messengers; neurotransmitters microtechnology; microsystems; microelectronics; biosensors; chemical messengers; neurotransmitters
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Mirzaei, M.; Sawan, M. Microelectronics-Based Biosensors Dedicated to the Detection of Neurotransmitters: A Review. Sensors 2014, 14, 17981-18008.

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