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Sensors 2014, 14(9), 17686-17702; doi:10.3390/s140917686

Development of Clinically Relevant Implantable Pressure Sensors: Perspectives and Challenges

SINTEF ICT, Department of Microsystems and Nanotechnology, NO-0314 Oslo, Norway
Sunnaas Rehabilitation Hospital HF, NO-1450 Nesoddtangen, Norway
Author to whom correspondence should be addressed.
Received: 7 July 2014 / Revised: 20 August 2014 / Accepted: 10 September 2014 / Published: 22 September 2014
(This article belongs to the Special Issue Implantable Sensors)
View Full-Text   |   Download PDF [692 KB, uploaded 22 September 2014]


This review describes different aspects to consider when developing implantable pressure sensor systems. Measurement of pressure is in general highly important in clinical practice and medical research. Due to the small size, light weight and low energy consumption Micro Electro Mechanical Systems (MEMS) technology represents new possibilities for monitoring of physiological parameters inside the human body. Development of clinical relevant sensors requires close collaboration between technological experts and medical clinicians. Site of operation, size restrictions, patient safety, and required measurement range and resolution, are only some conditions that must be taken into account. An implantable device has to operate under very hostile conditions. Long-term in vivo pressure measurements are particularly demanding because the pressure sensitive part of the sensor must be in direct or indirect physical contact with the medium for which we want to detect the pressure. New sensor packaging concepts are demanded and must be developed through combined effort between scientists in MEMS technology, material science, and biology. Before launching a new medical device on the market, clinical studies must be performed. Regulatory documents and international standards set the premises for how such studies shall be conducted and reported. View Full-Text
Keywords: implantable MEMS; pressure; sensor design; protective coatings; clinical relevance; clinical study implantable MEMS; pressure; sensor design; protective coatings; clinical relevance; clinical study
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Clausen, I.; Glott, T. Development of Clinically Relevant Implantable Pressure Sensors: Perspectives and Challenges. Sensors 2014, 14, 17686-17702.

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