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Automated Feature Set Selection and Its Application to MCC Identification in Digital Mammograms for Breast Cancer Detection
Department of Radiology, China Medical University Hospital, Taichung 404, Taiwan
Department of Electrical Engineering, National Chia-Yi University, Chiayi 600, Taiwan
Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung 404, Taiwan
* Authors to whom correspondence should be addressed.
Received: 16 February 2013; in revised form: 18 March 2013 / Accepted: 2 April 2013 / Published: 11 April 2013
Abstract: We propose a fully automated algorithm that is able to select a discriminative feature set from a training database via sequential forward selection (SFS), sequential backward selection (SBS), and F-score methods. We applied this scheme to microcalcifications cluster (MCC) detection in digital mammograms for early breast cancer detection. The system was able to select features fully automatically, regardless of the input training mammograms used. We tested the proposed scheme using a database of 111 clinical mammograms containing 1,050 microcalcifications (MCs). The accuracy of the system was examined via a free response receiver operating characteristic (fROC) curve of the test dataset. The system performance for MC identifications was Az = 0.9897, the sensitivity was 92%, and 0.65 false positives (FPs) were generated per image for MCC detection.
Keywords: mammography; clustered microcalcification; texture features; support vector machines
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MDPI and ACS Style
Huang, Y.-J.; Chan, D.-Y.; Cheng, D.-C.; Ho, Y.-J.; Tsai, P.-P.; Shen, W.-C.; Chen, R.-F. Automated Feature Set Selection and Its Application to MCC Identification in Digital Mammograms for Breast Cancer Detection. Sensors 2013, 13, 4855-4875.
Huang Y-J, Chan D-Y, Cheng D-C, Ho Y-J, Tsai P-P, Shen W-C, Chen R-F. Automated Feature Set Selection and Its Application to MCC Identification in Digital Mammograms for Breast Cancer Detection. Sensors. 2013; 13(4):4855-4875.
Huang, Yi-Jhe; Chan, Ding-Yuan; Cheng, Da-Chuan; Ho, Yung-Jen; Tsai, Po-Pang; Shen, Wu-Chung; Chen, Rui-Fen. 2013. "Automated Feature Set Selection and Its Application to MCC Identification in Digital Mammograms for Breast Cancer Detection." Sensors 13, no. 4: 4855-4875.