Abstract: In this study, time-resolved optical coherence tomography (OCT) scanning images of the process of water diffusion in the skin that illustrate the enhancement in the backscattered intensities due to the increased water concentration are presented. In our experiments, the water concentration in the skin was increased by soaking the hand in water, and the same region of the skin was scanned and measured with the OCT system and a commercial moisture monitor every three minutes. To quantitatively analyze the moisture-related optical properties and the velocity of water diffusion in human skin, the attenuation coefficients of the skin, including the epidermis and dermis layers, were evaluated. Furthermore, the evaluated attenuation coefficients were compared with the measurements made using the commercial moisture monitor. The results demonstrate that the attenuation coefficient increases as the water concentration increases. Furthermore, by evaluating the positions of center-of mass of the backscattered intensities from OCT images, the diffusion velocity can be estimated. In contrast to the commercial moisture monitor, OCT can provide three-dimensional structural images of the skin and characterize its optical property, which together can be used to observe morphological changes and quantitatively evaluate the moisture-related attenuation coefficients in different skin layers.
This is an open access article distributed under the
Creative Commons Attribution License which permits unrestricted use, distribution,
and reproduction in any medium, provided the original work is properly cited.
Export to BibTeX
MDPI and ACS Style
Lee, C.-K.; Tsai, M.-T.; Chang, F.-Y.; Yang, C.-H.; Shen, S.-C.; Yuan, O.; Yang, C.-H. Evaluation of Moisture-Related Attenuation Coefficient and Water Diffusion Velocity in Human Skin Using Optical Coherence Tomography. Sensors 2013, 13, 4041-4050.
Lee C-K, Tsai M-T, Chang F-Y, Yang C-H, Shen S-C, Yuan O, Yang C-H. Evaluation of Moisture-Related Attenuation Coefficient and Water Diffusion Velocity in Human Skin Using Optical Coherence Tomography. Sensors. 2013; 13(4):4041-4050.
Lee, Cheng-Kuang; Tsai, Meng-Tsan; Chang, Feng-Yu; Yang, Chih-Hsun; Shen, Su-Chin; Yuan, Ouyang; Yang, Chih-He. 2013. "Evaluation of Moisture-Related Attenuation Coefficient and Water Diffusion Velocity in Human Skin Using Optical Coherence Tomography." Sensors 13, no. 4: 4041-4050.