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Sensors 2013, 13(12), 16672-16681; doi:10.3390/s131216672
Article

Fabrication of a Microneedle/CNT Hierarchical Micro/Nano Surface Electrochemical Sensor and Its In-Vitro Glucose Sensing Characterization

1
, 1
, 2
 and 1,*
Received: 18 October 2013; in revised form: 14 November 2013 / Accepted: 22 November 2013 / Published: 4 December 2013
(This article belongs to the Section Physical Sensors)
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Abstract: We report fabrication of a microneedle-based three-electrode integrated electrochemical sensor and in-vitro characterization of this sensor for glucose sensing applications. A piece of silicon was sequentially dry and wet etched to form a 15 × 15 array of tall (approximately 380 µm) sharp silicon microneedles. Iron catalyst was deposited through a SU-8 shadow mask to form the working electrode and counter electrode. A multi-walled carbon nanotube forest was grown directly on the silicon microneedle array and platinum nano-particles were electrodeposited. Silver was deposited on the Si microneedle array through another shadow mask and chlorinated to form a Ag/AgCl reference electrode. The 3-electrode electrochemical sensor was tested for various glucose concentrations in the range of 3~20 mM in 0.01 M phosphate buffered saline (PBS) solution. The sensor’s amperometric response to the glucose concentration is linear and its sensitivity was found to be 17.73 ± 3 μA/mM-cm2. This microneedle-based sensor has a potential to be used for painless diabetes testing applications.
Keywords: microneedle; glucose sensing; nanoparticle microneedle; glucose sensing; nanoparticle
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Yoon, Y.; Lee, G.S.; Yoo, K.; Lee, J.-B. Fabrication of a Microneedle/CNT Hierarchical Micro/Nano Surface Electrochemical Sensor and Its In-Vitro Glucose Sensing Characterization. Sensors 2013, 13, 16672-16681.

AMA Style

Yoon Y, Lee GS, Yoo K, Lee J-B. Fabrication of a Microneedle/CNT Hierarchical Micro/Nano Surface Electrochemical Sensor and Its In-Vitro Glucose Sensing Characterization. Sensors. 2013; 13(12):16672-16681.

Chicago/Turabian Style

Yoon, Youngsam; Lee, Gil S.; Yoo, Koangki; Lee, Jeong-Bong. 2013. "Fabrication of a Microneedle/CNT Hierarchical Micro/Nano Surface Electrochemical Sensor and Its In-Vitro Glucose Sensing Characterization." Sensors 13, no. 12: 16672-16681.


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