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Sensors 2012, 12(9), 11505-11526; doi:10.3390/s120911505
Review

Recent Advances in Paper-Based Sensors

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Received: 16 July 2012; in revised form: 13 August 2012 / Accepted: 14 August 2012 / Published: 24 August 2012
(This article belongs to the Section Physical Sensors)
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Abstract: Paper-based sensors are a new alternative technology for fabricating simple, low-cost, portable and disposable analytical devices for many application areas including clinical diagnosis, food quality control and environmental monitoring. The unique properties of paper which allow passive liquid transport and compatibility with chemicals/biochemicals are the main advantages of using paper as a sensing platform. Depending on the main goal to be achieved in paper-based sensors, the fabrication methods and the analysis techniques can be tuned to fulfill the needs of the end-user. Current paper-based sensors are focused on microfluidic delivery of solution to the detection site whereas more advanced designs involve complex 3-D geometries based on the same microfluidic principles. Although paper-based sensors are very promising, they still suffer from certain limitations such as accuracy and sensitivity. However, it is anticipated that in the future, with advances in fabrication and analytical techniques, that there will be more new and innovative developments in paper-based sensors. These sensors could better meet the current objectives of a viable low-cost and portable device in addition to offering high sensitivity and selectivity, and multiple analyte discrimination. This paper is a review of recent advances in paper-based sensors and covers the following topics: existing fabrication techniques, analytical methods and application areas. Finally, the present challenges and future outlooks are discussed.
Keywords: paper; sensor; device; microfluidics; lab-on-a-chip; diagnostics; analytical paper; sensor; device; microfluidics; lab-on-a-chip; diagnostics; analytical
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Liana, D.D.; Raguse, B.; Gooding, J.J.; Chow, E. Recent Advances in Paper-Based Sensors. Sensors 2012, 12, 11505-11526.

AMA Style

Liana DD, Raguse B, Gooding JJ, Chow E. Recent Advances in Paper-Based Sensors. Sensors. 2012; 12(9):11505-11526.

Chicago/Turabian Style

Liana, Devi D.; Raguse, Burkhard; Gooding, J. Justin; Chow, Edith. 2012. "Recent Advances in Paper-Based Sensors." Sensors 12, no. 9: 11505-11526.


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