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Sensors 2012, 12(7), 9687-9696; doi:10.3390/s120709687
Article

A Novel Instrumentation Circuit for Electrochemical Measurements

1
,
2,* , 2
 and
3
1 Department of Optometry, Chung Hwa University of Medical Technology, Tainan 717, Taiwan 2 Department of Electronic Engineering, National Kaohsiung University of Applied Science, Kaohsiung 807, Taiwan 3 General Education Center, Chung Hwa University of Medical Technology, Tainan 717, Taiwan
* Author to whom correspondence should be addressed.
Received: 27 April 2012 / Revised: 9 June 2012 / Accepted: 9 July 2012 / Published: 17 July 2012
(This article belongs to the Section Biosensors)
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Abstract

In this paper, a novel signal processing circuit which can be used for the measurement of H+ ion and urea concentration is presented. A potentiometric method is used to detect the concentrations of H+ ions and urea by using H+ ion-selective electrodes and urea electrodes, respectively. The experimental data shows that this measuring structure has a linear pH response for the concentration range within pH 2 and 12, and the dynamic range for urea concentration measurement is in the range of 0.25 to 64 mg/dL. The designed instrumentation circuit possesses a calibration function and it can be applied to different sensing electrodes for electrochemical analysis. It possesses the advantageous properties of being multi-purpose, easy calibration and low cost.
Keywords: instrumentation; biosensor; electrochemical measurement; multi-purpose instrumentation; biosensor; electrochemical measurement; multi-purpose
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Yin, L.-T.; Wang, H.-Y.; Lin, Y.-C.; Huang, W.-C. A Novel Instrumentation Circuit for Electrochemical Measurements. Sensors 2012, 12, 9687-9696.

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