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Sensors 2012, 12(7), 9687-9696; doi:10.3390/s120709687

A Novel Instrumentation Circuit for Electrochemical Measurements

2,* , 2
1 Department of Optometry, Chung Hwa University of Medical Technology, Tainan 717, Taiwan 2 Department of Electronic Engineering, National Kaohsiung University of Applied Science, Kaohsiung 807, Taiwan 3 General Education Center, Chung Hwa University of Medical Technology, Tainan 717, Taiwan
* Author to whom correspondence should be addressed.
Received: 27 April 2012 / Revised: 9 June 2012 / Accepted: 9 July 2012 / Published: 17 July 2012
(This article belongs to the Section Biosensors)
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In this paper, a novel signal processing circuit which can be used for the measurement of H+ ion and urea concentration is presented. A potentiometric method is used to detect the concentrations of H+ ions and urea by using H+ ion-selective electrodes and urea electrodes, respectively. The experimental data shows that this measuring structure has a linear pH response for the concentration range within pH 2 and 12, and the dynamic range for urea concentration measurement is in the range of 0.25 to 64 mg/dL. The designed instrumentation circuit possesses a calibration function and it can be applied to different sensing electrodes for electrochemical analysis. It possesses the advantageous properties of being multi-purpose, easy calibration and low cost.
Keywords: instrumentation; biosensor; electrochemical measurement; multi-purpose instrumentation; biosensor; electrochemical measurement; multi-purpose
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Yin, L.-T.; Wang, H.-Y.; Lin, Y.-C.; Huang, W.-C. A Novel Instrumentation Circuit for Electrochemical Measurements. Sensors 2012, 12, 9687-9696.

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