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Sensors 2012, 12(7), 9687-9696; doi:10.3390/s120709687

A Novel Instrumentation Circuit for Electrochemical Measurements

Department of Optometry, Chung Hwa University of Medical Technology, Tainan 717, Taiwan
Department of Electronic Engineering, National Kaohsiung University of Applied Science, Kaohsiung 807, Taiwan
General Education Center, Chung Hwa University of Medical Technology, Tainan 717, Taiwan
Author to whom correspondence should be addressed.
Received: 27 April 2012 / Revised: 9 June 2012 / Accepted: 9 July 2012 / Published: 17 July 2012
(This article belongs to the Section Biosensors)
View Full-Text   |   Download PDF [350 KB, uploaded 21 June 2014]   |  


In this paper, a novel signal processing circuit which can be used for the measurement of H+ ion and urea concentration is presented. A potentiometric method is used to detect the concentrations of H+ ions and urea by using H+ ion-selective electrodes and urea electrodes, respectively. The experimental data shows that this measuring structure has a linear pH response for the concentration range within pH 2 and 12, and the dynamic range for urea concentration measurement is in the range of 0.25 to 64 mg/dL. The designed instrumentation circuit possesses a calibration function and it can be applied to different sensing electrodes for electrochemical analysis. It possesses the advantageous properties of being multi-purpose, easy calibration and low cost. View Full-Text
Keywords: instrumentation; biosensor; electrochemical measurement; multi-purpose instrumentation; biosensor; electrochemical measurement; multi-purpose

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Yin, L.-T.; Wang, H.-Y.; Lin, Y.-C.; Huang, W.-C. A Novel Instrumentation Circuit for Electrochemical Measurements. Sensors 2012, 12, 9687-9696.

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