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• Zhou, Y
• Chiu, C
• Liang, H
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• Chiu, C
• Liang, H
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• Chiu, C
• Liang, H

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Sensors 2012, 12(11), 15036-15062; doi:10.3390/s121115036

Review

Interfacial Structures and Properties of Organic Materials for Biosensors: An Overview

Yan Zhou ¹ , Cheng-Wei Chiu ²  and Hong Liang ^1,2,*

¹ Materials Science and Engineering, Texas A&M University, College Station, TX 77843, USA ² Department of Mechanical Engineering, Texas A&M University, College Station, TX 77843, USA

* Author to whom correspondence should be addressed.

Received: 21 September 2012; in revised form: 31 October 2012 / Accepted: 2 November 2012 / Published: 6 November 2012

(This article belongs to the Special Issue Organics and Metal Oxide Hybrid Sensors)

Download PDF Full-Text [602 KB, uploaded 6 November 2012 11:50 CET]

Abstract: The capabilities of biosensors for bio-environmental monitoring have profound influences on medical, pharmaceutical, and environmental applications. This paper provides an overview on the background and applications of the state-of-the-art biosensors. Different types of biosensors are summarized and sensing mechanisms are discussed. A review of organic materials used in biosensors is given. Specifically, this review focuses on self-assembled monolayers (SAM) due to their high sensitivity and high versatility. The kinetics, chemistry, and the immobilization strategies of biomolecules are discussed. Other representative organic materials, such as graphene, carbon nanotubes (CNTs), and conductive polymers are also introduced in this review.

Keywords: biosensor; interfacial properties; organic materials

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