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Sensors 2012, 12(11), 14604-14611; doi:10.3390/s121114604

Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors

1 Istituto di Fisica Applicata Nello Carrara (IFAC CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Firenze, Italy 2 Centro Studi e Ricerche e Museo Storico della Fisica Enrico Fermi, Piazza del Viminale 1, 00184 Roma, Italy
* Author to whom correspondence should be addressed.
Received: 26 September 2012 / Revised: 24 October 2012 / Accepted: 25 October 2012 / Published: 30 October 2012
(This article belongs to the Special Issue State-of-the-Art Sensors Technology in Italy 2012)
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Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
Keywords: whispering gallery mode resonators; immunosensors; Eudragit whispering gallery mode resonators; immunosensors; Eudragit
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Giannetti, A.; Berneschi, S.; Baldini, F.; Cosi, F.; Conti, G.N.; Soria, S. Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors. Sensors 2012, 12, 14604-14611.

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