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Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors
Istituto di Fisica Applicata Nello Carrara (IFAC CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Firenze, Italy
Centro Studi e Ricerche e Museo Storico della Fisica Enrico Fermi, Piazza del Viminale 1, 00184 Roma, Italy
* Author to whom correspondence should be addressed.
Received: 26 September 2012; in revised form: 24 October 2012 / Accepted: 25 October 2012 / Published: 30 October 2012
Abstract: Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
Keywords: whispering gallery mode resonators; immunosensors; Eudragit
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MDPI and ACS Style
Giannetti, A.; Berneschi, S.; Baldini, F.; Cosi, F.; Conti, G.N.; Soria, S. Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors. Sensors 2012, 12, 14604-14611.
Giannetti A, Berneschi S, Baldini F, Cosi F, Conti GN, Soria S. Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors. Sensors. 2012; 12(11):14604-14611.
Giannetti, Ambra; Berneschi, Simone; Baldini, Francesco; Cosi, Franco; Conti, Gualtiero N.; Soria, Silvia. 2012. "Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors." Sensors 12, no. 11: 14604-14611.