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Microfluidics-Based Lab-on-Chip Systems in DNA-Based Biosensing: An Overview
Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Department of Science Laboratory Technology, Hussaini Adamu Federal Polytechnic, Kazaure, Nigeria
* Author to whom correspondence should be addressed.
Received: 11 April 2011; in revised form: 11 May 2011 / Accepted: 23 May 2011 / Published: 27 May 2011
Abstract: Microfluidics-based lab-on-chip (LOC) systems are an active research area that is revolutionising high-throughput sequencing for the fast, sensitive and accurate detection of a variety of pathogens. LOCs also serve as portable diagnostic tools. The devices provide optimum control of nanolitre volumes of fluids and integrate various bioassay operations that allow the devices to rapidly sense pathogenic threat agents for environmental monitoring. LOC systems, such as microfluidic biochips, offer advantages compared to conventional identification procedures that are tedious, expensive and time consuming. This paper aims to provide a broad overview of the need for devices that are easy to operate, sensitive, fast, portable and sufficiently reliable to be used as complementary tools for the control of pathogenic agents that damage the environment.
Keywords: microfluidics; lab on chip; environment
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Dutse, S.W.; Yusof, N.A. Microfluidics-Based Lab-on-Chip Systems in DNA-Based Biosensing: An Overview. Sensors 2011, 11, 5754-5768.
Dutse SW, Yusof NA. Microfluidics-Based Lab-on-Chip Systems in DNA-Based Biosensing: An Overview. Sensors. 2011; 11(6):5754-5768.
Dutse, Sabo Wada; Yusof, Nor Azah. 2011. "Microfluidics-Based Lab-on-Chip Systems in DNA-Based Biosensing: An Overview." Sensors 11, no. 6: 5754-5768.