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Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors
Graduate School of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu, Kitakyushu 808-0135, Japan
Chitose Technical Center, Nihon Dempa Kogyo Co. Ltd., 1-3-1, Minami-Chitose, Hokkaido 066-0009, Japan
* Author to whom correspondence should be addressed.
Received: 1 December 2010; in revised form: 30 December 2010 / Accepted: 10 January 2011 / Published: 20 January 2011
Abstract: A respiratory monitoring system based on a quartz crystal microbalance (QCM) sensor with a functional film was designed and investigated. Porphyrins 5,10,15,20-tetrakis-(4-sulfophenyl)-21H,23H-porphine (TSPP) and 5,10,15,20-tetrakis-(4-sulfophenyl)-21H, 23H-porphine manganese (III) chloride (MnTSPP) used as sensitive elements were assembled with a poly(diallyldimethyl ammonium chloride) (PDDA). Films were deposited on the QCM resonators using layer-by-layer method in order to develop the sensor. The developed system, in which the sensor response reflects lung movements, was able to track human respiration providing respiratory rate (RR) and respiratory pattern (RP). The sensor system was tested on healthy volunteers to compare RPs and calculate RRs. The operation principle of the proposed system is based on the fast adsorption/desorption behavior of water originated from human breath into the sensor films deposited on the QCM electrode.
Keywords: respiratory monitoring; quartz crystal microbalance; porphyrin based thin films; layer-by layer approach; sensor array
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MDPI and ACS Style
Selyanchyn, R.; Korposh, S.; Wakamatsu, S.; Lee, S.-W. Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors. Sensors 2011, 11, 1177-1191.
Selyanchyn R, Korposh S, Wakamatsu S, Lee S-W. Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors. Sensors. 2011; 11(1):1177-1191.
Selyanchyn, Roman; Korposh, Serhiy; Wakamatsu, Shunichi; Lee, Seung-Woo. 2011. "Respiratory Monitoring by Porphyrin Modified Quartz Crystal Microbalance Sensors." Sensors 11, no. 1: 1177-1191.