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Sensors 2011, 11(1), 1105-1176; doi:10.3390/s110101105

Advances in Electronic-Nose Technologies Developed for Biomedical Applications

Southern Hardwoods Laboratory, Center for Bottomland Hardwoods Research, Southern Research Station, USDA Forest Service, 432 Stoneville Road, Stoneville, MS 38776, USA
Dipartimento di Produzione Vegetale, Università degli Studi di Milano, Via Celoria 2, 20133 Milan, Italy
Author to whom correspondence should be addressed.
Received: 30 September 2010 / Revised: 8 December 2010 / Accepted: 10 December 2010 / Published: 19 January 2011
(This article belongs to the Special Issue Sensors in Biomechanics and Biomedicine)
View Full-Text   |   Download PDF [346 KB, 21 June 2014; original version 21 June 2014]


The research and development of new electronic-nose applications in the biomedical field has accelerated at a phenomenal rate over the past 25 years. Many innovative e-nose technologies have provided solutions and applications to a wide variety of complex biomedical and healthcare problems. The purposes of this review are to present a comprehensive analysis of past and recent biomedical research findings and developments of electronic-nose sensor technologies, and to identify current and future potential e-nose applications that will continue to advance the effectiveness and efficiency of biomedical treatments and healthcare services for many years. An abundance of electronic-nose applications has been developed for a variety of healthcare sectors including diagnostics, immunology, pathology, patient recovery, pharmacology, physical therapy, physiology, preventative medicine, remote healthcare, and wound and graft healing. Specific biomedical e-nose applications range from uses in biochemical testing, blood-compatibility evaluations, disease diagnoses, and drug delivery to monitoring of metabolic levels, organ dysfunctions, and patient conditions through telemedicine. This paper summarizes the major electronic-nose technologies developed for healthcare and biomedical applications since the late 1980s when electronic aroma detection technologies were first recognized to be potentially useful in providing effective solutions to problems in the healthcare industry.
Keywords: artificial olfaction; disease diagnoses; electronic aroma detection; e-nose; healthcare applications artificial olfaction; disease diagnoses; electronic aroma detection; e-nose; healthcare applications
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Wilson, A.D.; Baietto, M. Advances in Electronic-Nose Technologies Developed for Biomedical Applications. Sensors 2011, 11, 1105-1176.

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