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Sensors 2010, 10(2), 1216-1231; doi:10.3390/s100201216

ZnO-Based Amperometric Enzyme Biosensors

School of Electronic Science and Engineering, Southeast University, Nanjing 210096, China
State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
Authors to whom correspondence should be addressed.
Received: 16 December 2009 / Revised: 19 January 2010 / Accepted: 19 January 2010 / Published: 1 February 2010
(This article belongs to the Special Issue Metal-Oxide Based Nanosensors)
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Nanostructured ZnO with its unique properties could provide a suitable microenvironment for immobilization of enzymes while retaining their biological activity, and thus lead to an expanded use of this nanomaterial for the construction of electrochemical biosensors with enhanced analytical performance. ZnO-based enzyme electrochemical biosensors are summarized in several tables for an easy overview according to the target biosensing analyte (glucose, hydrogen peroxide, phenol and cholesterol), respectively. Moreover, recent developments in enzyme electrochemical biosensors based on ZnO nanomaterials are reviewed with an emphasis on the fabrications and features of ZnO, approaches for biosensor construction (e.g., modified electrodes and enzyme immobilization) and biosensor performances.
Keywords: ZnO; electrochemical; enzyme biosensors ZnO; electrochemical; enzyme biosensors
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Zhao, Z.; Lei, W.; Zhang, X.; Wang, B.; Jiang, H. ZnO-Based Amperometric Enzyme Biosensors. Sensors 2010, 10, 1216-1231.

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