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Sensors 2010, 10(11), 10339-10355; doi:10.3390/s101110339

Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings

* ,
Department of Micro- and Nanotechnology, Technical University of Denmark, DTU Nanotech, Building 345E, Kgs. Lyngby, Denmark
* Author to whom correspondence should be addressed.
Received: 18 October 2010 / Revised: 28 October 2010 / Accepted: 15 November 2010 / Published: 17 November 2010
(This article belongs to the Special Issue State-of-the-Art Sensors Technology in Denmark)
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In this paper we discuss the fabrication and characterization of three dimensional (3D) micro- and nanoelectrodes with the goal of using them for extra- and intracellular studies. Two different types of electrodes will be described: high aspect ratio microelectrodes for studying the communication between cells and ultimately for brain slice recordings and small nanoelectrodes for highly localized measurements and ultimately for intracellular studies. Electrical and electrochemical characterization of these electrodes as well as the results of PC12 cell differentiation on chip will be presented and discussed.
Keywords: 3D electrodes; fabrication; neuron differentiation on chip 3D electrodes; fabrication; neuron differentiation on chip
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Dimaki, M.; Vazquez, P.; Olsen, M.H.; Sasso, L.; Rodriguez-Trujillo, R.; Vedarethinam, I.; Svendsen, W.E. Fabrication and Characterization of 3D Micro- and Nanoelectrodes for Neuron Recordings. Sensors 2010, 10, 10339-10355.

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