Special Issue "State-of-the-Art Sensors Technology in Denmark"
QuicklinksA special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "State-of-the-Art Sensors Technologies".
Deadline for manuscript submissions: 30 April 2010
Special Issue Editor
Guest Editor
Prof. Dr. Jørgen Kjems
Department of Molecular Biology, University of Aarhus, C.F. Mollers Alle, DK-8000 Aarhus C, Denmark
Website: http://www.rnai.dk/jk/index.htm
E-Mail:
Interests: RNA and protein biochemistry; RNA splicing; RNA interference; siRNA delivery and therapeutic applications; aptamer technology; miRNA analysis; eukaryotic cell biology; viruses; gene expression control; fluorescence techniques in cell biology; biosensors; bioimaging; DNA; RNA and protein based nanotechnologies
Published Papers
Special Issue Information
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.
Keywords
- biosensors
- chemical sensors
- physical sensors
- remote sensing sensors
Planned Papers
Type of Paper: Review
Title: The Use of Dynamic Fluorescence Imaging in the Study of Volume Regulation
Authors: T. K. Klausen, E. K. Hoffmann and S. F. Pedersen
Affiliation: Dept. of Biology, University of Copenhagen, 13, Universitetsparken, DK-2100 Copenhagen, Denmark; E-Mail: sfpedersen@bio.ku.dk
Abstract: Fluorescence-based methods are increasingly replacing chemical and biophysical techniques in the study of transmembrane ion transport. This has revolutionized the understanding of ion transport, not least by greatly increasing temporal and spatial resolution and allowing simultaneous measurements of multiple parameters. However, these techniques are also prone to serious artifacts. Cell volume regulation is a complex, dynamic process involving a fine-tuned temporal sequence of altered activity of several transmembrane transport systems and consequent changes in the cellular content of osmolytes, water content, cell volume, and membrane potential. Here, we review strengths and weaknesses of fluorescent techniques for the study of cell volume regulation and cover the pitfalls introduced by a changing cytosolic volume. The review will cover fluorescent techniques for measuring of various ions, pH, membrane potential and - of course - cell volume and the perspectives of genetically encoded fluorescent sensors.
Type of Paper: Review
Title: Electrochemical Biosensors for Medical Applications
Author: Elena E. Ferapontova
Affiliation: Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Ny Munkegade 1521, DK-8000 Aarhus C, Denmark; E-Mail: e_ferapontova@chem.au.dk
Abstract: Biosensor technologies have become increasingly important in medicine and molecular diagnostics, for analysis of genetic disorders, treatment of bacterial and viral infections, for studies of neorodegenerative diseases and such conditions as diabetes and asthma. As an alternative to the existing approaches, electrochemical techniques allow the development of extremely sensitive and accurate yet simple, inexpensive and robust biosensing platforms. Here I overview and analyze the existing electrochemical approaches and latest trends in gene and cancer biomarkers analysis and bioanalysis of small molecules of medical interest. Benefits of electrochemical technologies exploiting nucleic acid, aptamers and enzymes as biorecognition units are discussed.
Last update: 12 February 2010