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Sensors 2010, 10(10), 9397-9406; doi:10.3390/s101009397
Article

E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing

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Received: 1 September 2010 / Revised: 30 September 2010 / Accepted: 9 October 2010 / Published: 20 October 2010
(This article belongs to the Section Physical Sensors)
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Abstract

Electron beam lithography (EBL) was used to directly pattern periodic gold nanodot arrays on optical fiber tips. Localized surface plasmon resonance of the E-beam patterned gold nanodot arrays on optical fiber tips was utilized for biochemical sensing. The advantage of the optical fiber based localized surface plasmon resonance (LSPR) sensors is the convenience to work with and work in harsh environments. An optical fiber tip LSPR refractive index sensor of 196 nm per refractive index unit (RIU) sensitivity has been demonstrated. The affinity sensing property of the fiber tip sensor was demonstrated using biotin/streptavidin as the receptor/analyte. The detection limit for streptavidin was determined to be 6 pM.
Keywords: localized surface plasmon resonance sensor; nanofabrication; fiber optic biosensor localized surface plasmon resonance sensor; nanofabrication; fiber optic biosensor
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Lin, Y.; Zou, Y.; Mo, Y.; Guo, J.; Lindquist, R.G. E-Beam Patterned Gold Nanodot Arrays on Optical Fiber Tips for Localized Surface Plasmon Resonance Biochemical Sensing. Sensors 2010, 10, 9397-9406.

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