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Nanomaterials as Analytical Tools for Genosensors
King Abdullah Institute for Nanotechnology, King Saud University, Riyadh-11451, P.O Box-2454, Saudi Arabia
* Author to whom correspondence should be addressed.
Received: 12 December 2009; in revised form: 8 January 2010 / Accepted: 11 January 2010 / Published: 26 January 2010
Abstract: Nanomaterials are being increasingly used for the development of electrochemical DNA biosensors, due to the unique electrocatalytic properties found in nanoscale materials. They offer excellent prospects for interfacing biological recognition events with electronic signal transduction and for designing a new generation of bioelectronic devices exhibiting novel functions. In particular, nanomaterials such as noble metal nanoparticles (Au, Pt), carbon nanotubes (CNTs), magnetic nanoparticles, quantum dots and metal oxide nanoparticles have been actively investigated for their applications in DNA biosensors, which have become a new interdisciplinary frontier between biological detection and material science. In this article, we address some of the main advances in this field over the past few years, discussing the issues and challenges with the aim of stimulating a broader interest in developing nanomaterial-based biosensors and improving their applications in disease diagnosis and food safety examination.
Keywords: nanomaterials; oligonucleotides; ZnO; carbon nanotubes; conducting polymers
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Abu-Salah, K.M.; Alrokyan, S.A.; Khan, M.N.; Ansari, A.A. Nanomaterials as Analytical Tools for Genosensors. Sensors 2010, 10, 963-993.
Abu-Salah KM, Alrokyan SA, Khan MN, Ansari AA. Nanomaterials as Analytical Tools for Genosensors. Sensors. 2010; 10(1):963-993.
Abu-Salah, Khalid M.; Alrokyan, Salman A.; Khan, Muhammad Naziruddin; Ansari, Anees Ahmad. 2010. "Nanomaterials as Analytical Tools for Genosensors." Sensors 10, no. 1: 963-993.