Next Issue
Previous Issue

E-Mail Alert

Add your e-mail address to receive forthcoming issues of this journal:

Journal Browser

Journal Browser

Table of Contents

Molbank, Volume 2015, Issue 4 (December 2015)

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
View options order results:
result details:
Displaying articles 1-14
Export citation of selected articles as:

Other

Open AccessShort Note 1,1′-{1,4-Phenylene bis[3-(6-chloro-2-methyl-4-phenylquinolin-3-yl)-4,5-dihydro-1H-pyrazole-5,1-diyl]}dibutan-1-one
Molbank 2015, 2015(4), M868; doi:10.3390/M868
Received: 14 July 2015 / Revised: 12 September 2015 / Accepted: 22 September 2015 / Published: 5 October 2015
PDF Full-text (690 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A new polycyclic compound, 1,1′-{1,4-phenylene bis[3-(6-chloro-2-methyl-4-phenylquinolin-3-yl)-4,5-dihydro-1H-pyrazole-5,1-diyl]}dibutan-1-one (3) has been synthesized by cyclocondensation of (2E,2′E)-1,1′-bis(6-chloro-2-methyl-4-phenylquinolin-3-yl)-3,3′-(1,4-phenylene)diprop-2-en-1-one (2) and hydrazine hydrate in butanoic acid. The structure of this compound was established by elemental analysis, 1H-NMR, 13C-NMR, mass and IR spectroscopy. Full article
Figures

Open AccessShort Note 7-Iodo-1H-indole-3-carbonitrile
Molbank 2015, 2015(4), M869; doi:10.3390/M869
Received: 8 September 2015 / Revised: 8 October 2015 / Accepted: 13 October 2015 / Published: 23 October 2015
Cited by 1 | PDF Full-text (665 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
The title compound was prepared by a Friedel–Crafts acylation-oxime synthesis-decarboxylation/dehydration sequence starting from commercially available 7-iodoindole with 2-(7-iodo-1H-indol-3-yl)-2-oxoacetic acid as isolated intermediate. The structural identity of the title compound was proven by elemental analysis and spectroscopic methods (IR, NMR, EI-MS), and
[...] Read more.
The title compound was prepared by a Friedel–Crafts acylation-oxime synthesis-decarboxylation/dehydration sequence starting from commercially available 7-iodoindole with 2-(7-iodo-1H-indol-3-yl)-2-oxoacetic acid as isolated intermediate. The structural identity of the title compound was proven by elemental analysis and spectroscopic methods (IR, NMR, EI-MS), and purity was assessed by two independent HPLC methods. Full article
Figures

Open AccessShort Note 3-(3,4-Dihydroxyphenyl)-8-hydroxy-2H-chromen-2-one
Molbank 2015, 2015(4), M870; doi:10.3390/M870
Received: 30 September 2015 / Revised: 21 October 2015 / Accepted: 27 October 2015 / Published: 29 October 2015
PDF Full-text (687 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
We report a novel protocol for the synthesis of 3-(3,4-dihydroxyphenyl)-8-hydroxy-2H-chromen-2-one via demethylation/delactonization/elimination/lactonization/ decarboxylation domino reaction sequence of diastereomeric mixture of cis- and trans-3-(2,3-dimethoxyphenyl)-6,7-dimethoxy-1-oxoisochroman-4-carboxylic acids in boiling HBr/AcOH. The structure of the target compound was established for the first time
[...] Read more.
We report a novel protocol for the synthesis of 3-(3,4-dihydroxyphenyl)-8-hydroxy-2H-chromen-2-one via demethylation/delactonization/elimination/lactonization/ decarboxylation domino reaction sequence of diastereomeric mixture of cis- and trans-3-(2,3-dimethoxyphenyl)-6,7-dimethoxy-1-oxoisochroman-4-carboxylic acids in boiling HBr/AcOH. The structure of the target compound was established for the first time by means of spectral methods such as 1H-, 13C-, DEPT-135-NMR, IR and HRMS. Full article
Figures

Open AccessShort Note 4-Chloro-2,3,5-trifluorobenzoic Acid
Molbank 2015, 2015(4), M871; doi:10.3390/M871
Received: 27 May 2015 / Revised: 28 October 2015 / Accepted: 29 October 2015 / Published: 3 November 2015
PDF Full-text (663 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A new tetrahalogenated benzoic acid 4-chloro-2,3,5-trifluorobenzoic acid was synthesized from methyl 2,3,4,5-tetrafluorobenzoate via three steps. The structure of the newly synthesized compound was established by FTIR, NMR, MS and elemental analysis. Full article
Figures

Open AccessShort Note (Z)-3-Amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
Molbank 2015, 2015(4), M872; doi:10.3390/M872
Received: 25 September 2015 / Revised: 27 October 2015 / Accepted: 2 November 2015 / Published: 4 November 2015
PDF Full-text (694 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
3-Aminorhodanine reacts with aldehydes to form either 5-[(aryl)alkylidene]-substituted products or Schiff bases or derivatives substituted at both the 3-amino group and the 5-methylene group, depending on the reaction conditions. In this note, synthesis and characterization of 3-amino-5-(pyridin-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is reported. Full article
Figures

Open AccessShort Note 1-[2,3-Bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea
Molbank 2015, 2015(4), M873; doi:10.3390/M873
Received: 29 September 2015 / Revised: 3 November 2015 / Accepted: 9 November 2015 / Published: 11 November 2015
PDF Full-text (665 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Starting from 2,3-bis(tetradecyloxy)propan-1-amine (1), the synthesis of the target compound 1-[2,3-bis(tetradecyloxy)propyl]-3-[2-(piperazin-1-yl)ethyl]urea (2) is reported. The title compound was characterized by 1H-NMR, 13C-NMR and ESI/MS analysis. Full article
Figures

Open AccessShort Note 1-(3-Iodopropyl)-4-methylquinolin-1-ium Iodide
Molbank 2015, 2015(4), M874; doi:10.3390/M874
Received: 17 September 2015 / Revised: 31 October 2015 / Accepted: 3 November 2015 / Published: 11 November 2015
PDF Full-text (646 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A solvent-free “one-pot” synthetic approach to 1-(3-iodopropyl)-4-methylquinolin-1-ium iodide is reported in the present work. The title compound is derived from N-alkylation of 4-methylquinoline with 1,3-diiodopropane proceeded at room temperature. The target quinolinium salt is obtained in a highly pure form. It’s structure was
[...] Read more.
A solvent-free “one-pot” synthetic approach to 1-(3-iodopropyl)-4-methylquinolin-1-ium iodide is reported in the present work. The title compound is derived from N-alkylation of 4-methylquinoline with 1,3-diiodopropane proceeded at room temperature. The target quinolinium salt is obtained in a highly pure form. It’s structure was evaluated by 1H-NMR, 13C-NMR, and DEPT135 spectra. Full article
Figures

Open AccessShort Note (8R,10aS)-Methyl 2,4-diamino-8-(tert-butyl)-6-oxo-6,8,10,10a-tetrahydrooxazolo[3′′,4′′:1′,5′]-pyrrolo[3′,4′:5,6]pyrido[2,3-d]pyrimidine-10a-carboxylate
Molbank 2015, 2015(4), M875; doi:10.3390/M875
Received: 21 September 2015 / Revised: 17 November 2015 / Accepted: 18 November 2015 / Published: 23 November 2015
Cited by 1 | PDF Full-text (735 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A fused polyheterocyclic derivative is available by annulation of a tetramate scaffold, and has been shown to have some Gram-negative, but not Gram-positive, antibacterial activity. Full article
Figures

Open AccessShort Note 1,4-Di(2-butoxycarbonyl-trans-vinyl)-2,5-dimethoxybenzene
Molbank 2015, 2015(4), M876; doi:10.3390/M876
Received: 8 September 2015 / Revised: 4 November 2015 / Accepted: 5 November 2015 / Published: 23 November 2015
PDF Full-text (662 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
The title compound 1,4-di(2-butoxycarbonyl-trans-vinyl)-2,5-dimethoxybenzene was synthesized in 94% yield through the Heck reaction between 2,5-diiodo-1,4-dimethoxybenzene and n-butyl acrylate, using bis(dibenzylideneacetone) palladium(0) as homogeneous catalyst. Full article
Figures

Open AccessShort Note N′-(1,3-Dithiolan-2-ylidene)-3-(phenylamino)propanehydrazide
Molbank 2015, 2015(4), M877; doi:10.3390/M877
Received: 24 September 2015 / Revised: 12 November 2015 / Accepted: 16 November 2015 / Published: 23 November 2015
PDF Full-text (681 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A synthesis of N′-(1,3-dithiolan-2-ylidene)-3-(phenylamino)propanehydrazide from 3-(phenylamino)propanehydrazide, carbon disulfide and 1,2-dibromoethane is reported. The title compound was characterized by 1H NMR, 13C NMR, ESI/MS, and elemental analysis. Full article
Figures

Open AccessShort Note Methyl (6-Ethyldibenzo[d,f][1,3]dioxepin-6-yl)acetate
Molbank 2015, 2015(4), M878; doi:10.3390/M878
Received: 26 October 2015 / Accepted: 19 November 2015 / Published: 24 November 2015
PDF Full-text (650 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Starting from 2,2'-dihydroxybiphenyl and an allenic ester, the title dibenzo-condensed dioxepine derivative was synthesized using a one-pot procedure. Full article
Figures

Open AccessShort Note 4-[3-(Pyridin-3-yl)prop-2-enoyl]phenyl 4-dodecyloxybenzoate
Molbank 2015, 2015(4), M879; doi:10.3390/M879
Received: 20 October 2015 / Revised: 19 November 2015 / Accepted: 19 November 2015 / Published: 2 December 2015
PDF Full-text (652 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Steglich esterification between 1-(4-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one and 4-dodecyloxybenzoic acid has produced a new compound, 4-[3-(pyridin-3-yl) prop-2-enoyl]phenyl 4-dodecyloxybenzoate. The title compound was characterized by IR and NMR analysis. Full article
Figures

Open AccessShort Note 9,19-Cyclolanost-24-en-3-one,21,23-epoxy-21,22-dihydroxy (21R, 22S, 23S) from the Leaves of Lansium domesticum Corr cv Kokossan
Molbank 2015, 2015(4), M880; doi:10.3390/M880
Received: 12 October 2015 / Revised: 26 November 2015 / Accepted: 1 December 2015 / Published: 4 December 2015
PDF Full-text (846 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A new cycloartan-type triterpenoid, 9,19-cyclolanost-24-en-3-one,21,23-epoxy-21,22-dihydroxy (21R, 22S, 23S), was isolated from the leaves of Lansium domesticum Corr cv kokossan. The chemical structure of 1 was elucidated on the basis of spectroscopic data, X-ray diffraction and comparison with those related compounds previously reported.
[...] Read more.
A new cycloartan-type triterpenoid, 9,19-cyclolanost-24-en-3-one,21,23-epoxy-21,22-dihydroxy (21R, 22S, 23S), was isolated from the leaves of Lansium domesticum Corr cv kokossan. The chemical structure of 1 was elucidated on the basis of spectroscopic data, X-ray diffraction and comparison with those related compounds previously reported. Full article
Figures

Open AccessShort Note Luteinizing Hormone Releasing Hormone/Galactose Core/Lipopeptide
Molbank 2015, 2015(4), M881; doi:10.3390/M881
Received: 28 September 2015 / Revised: 3 December 2015 / Accepted: 10 December 2015 / Published: 16 December 2015
PDF Full-text (662 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
A self-adjuvanting vaccine candidate comprising four copies of luteinizing hormone releasing hormone (LHRH), a galactose carrier/core and lipoamino acid based adjuvant was synthesized in 21% yield by a solid phase peptide synthesis, carbohydrate and Boc-chemistry methods. Full article
Figures

Back to Top